Donchin E, Herning R I
Electroencephalogr Clin Neurophysiol. 1975 Jan;38(1):51-68. doi: 10.1016/0013-4694(75)90210-2.
Cortical average evoked potentials were simulated by summing five damped sinusoids. The characteristics of these "evoked" responses could be manipulated by changing parameters of the sinusoids. The synthesized signals were mixed with noise processes whose power and band-width were manipulated. Thus data were generated to stimulate a variety of conditions which could conceivably occur in an experiment on evoked potentials. Stepwise discriminant analysis (BMD07M) has been applied to these simulated data in an attempt to determine the degree to which the program identifies, in a sensible manner, the differences we introduced into the synthesized evoked responses. The simulation results indicate that stepwise discriminant analysis can indeed be an efficacious tool in research on evoked potentials. The program does detect differences in evoked potentials. It can be used, with some reservations, to identify the components of an evoked potential which the experimental variables have affected. In a special set of simulations we have attempted to determine the degree to which stepwise discriminant analysis could serve to detect the presence or absence of an evoked potential. These simulations show that the score of an average evoked potential in the data. The implications of this finding to the use of evoked potentials in sensory sensitivity testing were evaluated in studies for the effect on them of stimulus intensity.
通过对五个阻尼正弦波求和来模拟皮层平均诱发电位。这些“诱发”反应的特征可以通过改变正弦波的参数来操控。将合成信号与功率和带宽可控的噪声过程相混合。由此生成的数据可用于模拟诱发电位实验中可能出现的各种情况。逐步判别分析（BMD07M）已应用于这些模拟数据，以确定该程序能在多大程度上合理地识别我们引入合成诱发电位中的差异。模拟结果表明，逐步判别分析确实可以成为诱发电位研究中的一种有效工具。该程序确实能检测到诱发电位的差异。在有一定保留的情况下，它可用于识别实验变量所影响的诱发电位成分。在一组特殊的模拟中，我们试图确定逐步判别分析能在多大程度上用于检测诱发电位的有无。这些模拟表明了数据中平均诱发电位的得分情况。在关于刺激强度对其影响的研究中，评估了这一发现对在感觉敏感性测试中使用诱发电位的意义。
