一项关于乙酰水杨酸在心肌梗死死亡率二级预防中的随机对照试验。
A randomized controlled trial of acetyl salicylic acid in the secondary prevention of mortality from myocardial infarction.
作者信息
Elwood P C, Cochrane A L, Burr M L, Sweetnam P M, Williams G, Welsby E, Hughes S J, Renton R
出版信息
Br Med J. 1974 Mar 9;1(5905):436-40. doi: 10.1136/bmj.1.5905.436.
Abstract
The results of a randomized controlled trial of a single daily dose of acetyl salicylic acid (aspirin) in the prevention of reinfarction in 1,239 men who had had a recent myocardial infarct were statistically inconclusive. Nevertheless, they showed a reduction in total mortality of 12% at six months and 25% at twelve months after admission to the trial. Further trials are urgently required to establish whether or not this effect is real.
摘要
一项针对1239名近期发生心肌梗死男性患者进行的随机对照试验，旨在研究每日单次剂量乙酰水杨酸（阿司匹林）预防再梗死的效果，该试验结果在统计学上尚无定论。然而，结果显示，在进入试验后的6个月时总死亡率降低了12%，12个月时降低了25%。迫切需要进一步试验以确定这种效果是否真实存在。
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A randomized controlled trial of acetyl salicylic acid in the secondary prevention of mortality from myocardial infarction.一项关于乙酰水杨酸在心肌梗死死亡率二级预防中的随机对照试验。
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