• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Methionine metabolism in mammals: the biochemical basis for homocystinuria.

作者信息

Finkelstein J D

出版信息

Metabolism. 1974 Apr;23(4):387-98. doi: 10.1016/0026-0495(74)90057-2.

DOI:10.1016/0026-0495(74)90057-2
PMID:4593752
Abstract
摘要

相似文献

1
Methionine metabolism in mammals: the biochemical basis for homocystinuria.哺乳动物中的甲硫氨酸代谢：同型胱氨酸尿症的生化基础。
Metabolism. 1974 Apr;23(4):387-98. doi: 10.1016/0026-0495(74)90057-2.
2
Homocystinuria: studies in tissue culture.同型胱氨酸尿症：组织培养研究
Pediatr Res. 1973 Jul;7(7):645-58. doi: 10.1203/00006450-197307000-00008.
3
Homocystinuria, vitamin B 6 , and folate: metabolic interrelationships and clinical significance.
J Pediatr. 1972 Nov;81(5):1014-8. doi: 10.1016/s0022-3476(72)80563-8.
4
Folate-responsive homocystinuria and "schizophrenia". A defect in methylation due to deficient 5,10-methylenetetrahydrofolate reductase activity.叶酸反应性同型胱氨酸尿症与“精神分裂症”。因5,10-亚甲基四氢叶酸还原酶活性不足导致的甲基化缺陷。
N Engl J Med. 1975 Mar 6;292(10):491-6. doi: 10.1056/NEJM197503062921001.
5
Homocystinuria due to cystathionine synthase deficiency: the effect of pyridoxine.由于胱硫醚合成酶缺乏所致的同型胱氨酸尿症：维生素B6的作用。
J Clin Invest. 1970 Sep;49(9):1762-73. doi: 10.1172/JCI106394.
6
Homocystinuria due to cystathionine synthase deficiency.由于胱硫醚合成酶缺乏所致的同型胱氨酸尿症。
Ann Intern Med. 1965 Dec;63(6):1117-42. doi: 10.7326/0003-4819-63-6-1117.
7
Methionine metabolism in man: development and deficiencies.
Clin Endocrinol Metab. 1974 Mar;3(1):37-55. doi: 10.1016/s0300-595x(74)80024-1.
8
Homocystinuria due to cystathionine synthase deficiency: enzymatic and ultrastructural studies.由于胱硫醚合成酶缺乏所致的同型胱氨酸尿症：酶学及超微结构研究
J Pediatr. 1974 Mar;84(3):381-90. doi: 10.1016/s0022-3476(74)80721-3.
9
Cystathionine synthase in tissue culture derived from human skin: enzyme defect in homocystinuria.人皮肤来源的组织培养中的胱硫醚合酶：同型胱氨酸尿症中的酶缺陷。
Science. 1968 May 31;160(3831):1007-9. doi: 10.1126/science.160.3831.1007.
10
Incorporation of methionine sulphur into cysteine in vitro by fibroblasts deficient in cystathionine synthetase.胱硫醚合成酶缺陷的成纤维细胞在体外将蛋氨酸硫掺入半胱氨酸的过程。
Arch Dis Child. 1969 Dec;44(238):779-80. doi: 10.1136/adc.44.238.779-b.

引用本文的文献

1
Identification and Functional Analysis of Cystathionine Beta-Synthase Gene Mutations in Chinese Families with Classical Homocystinuria.中国经典型同型胱氨酸尿症家系中胱硫醚β-合酶基因突变的鉴定与功能分析
Biomedicines. 2025 Apr 9;13(4):919. doi: 10.3390/biomedicines13040919.
2
Hyperhomocysteinemia: Clinical Insights.高同型半胱氨酸血症：临床见解
J Cent Nerv Syst Dis. 2020 Oct 9;12:1179573520962230. doi: 10.1177/1179573520962230. eCollection 2020.
3
Prevalence, characteristics, and costs of diagnosed homocystinuria, elevated homocysteine, and phenylketonuria in the United States: a retrospective claims-based comparison.
美国确诊的同型胱氨酸尿症、高同型半胱氨酸血症和苯丙酮尿症的流行情况、特征和费用：一项基于回顾性索赔的比较。
BMC Health Serv Res. 2020 Mar 6;20(1):183. doi: 10.1186/s12913-020-5054-5.
4
In utero alcohol exposure, epigenetic changes, and their consequences.子宫内酒精暴露、表观遗传变化及其后果。
Alcohol Res. 2013;35(1):37-46.
5
Inhibition of betaine-homocysteine S-methyltransferase in rats causes hyperhomocysteinemia and reduces liver cystathionine β-synthase activity and methylation capacity.在大鼠中抑制甜菜碱同型半胱氨酸 S-甲基转移酶会导致高同型半胱氨酸血症，并降低肝脏胱硫醚 β-合酶活性和甲基化能力。
Nutr Res. 2011 Jul;31(7):563-71. doi: 10.1016/j.nutres.2011.06.004.
6
Ginsenosides: are any of them candidates for drugs acting on the central nervous system?人参皂苷：它们中有任何一种是作用于中枢神经系统的药物候选物吗？
CNS Drug Rev. 2007 Winter;13(4):381-404. doi: 10.1111/j.1527-3458.2007.00023.x.
7
[Folate against hyperhomocysteinemia. A new approach for the prevention and therapy of alcoholism-associated disorders?].[叶酸对抗高同型半胱氨酸血症。一种预防和治疗酒精中毒相关疾病的新方法？]
Nervenarzt. 2004 May;75(5):425-30. doi: 10.1007/s00115-003-1606-2.
8
Homocystinuria: the effect of pyridoxine supplementation on cultured skin fibroblasts.同型胱氨酸尿症：补充吡哆醇对培养的皮肤成纤维细胞的影响。
J Inherit Metab Dis. 1981;4(1):7-9. doi: 10.1007/BF02263574.
9
Decreased rates of methionine synthesis by methylene tetrahydrofolate reductase-deficient fibroblasts and lymphoblasts.亚甲基四氢叶酸还原酶缺陷的成纤维细胞和淋巴细胞中甲硫氨酸合成速率降低。
J Clin Invest. 1981 Jun;67(6):1659-64. doi: 10.1172/jci110202.
10
Effect of vitamin B-6 (pyridoxine) deficiency on lung elastin cross-linking in perinatal and weanling rat pups.维生素B-6（吡哆醇）缺乏对围产期和断奶期幼鼠肺弹性蛋白交联的影响。
Biochem J. 1985 Jul 1;229(1):153-60. doi: 10.1042/bj2290153.