特布他林与沙丁胺醇气雾剂对可逆性气道阻塞患者心肺效应的比较
Comparison of cardiorespiratory effects of terbutaline and salbutamol aerosols in patients with reversible airways obstruction.
作者信息
Harris L
出版信息
Thorax. 1973 Sep;28(5):592-5. doi: 10.1136/thx.28.5.592.
Abstract
, , 592-595. The effects of pressurized aerosol administration of terbutaline were compared with those of salbutamol in 14 patients with at least 20% reversibility of airways obstruction. The two drugs were found to be equipotent bronchodilators in the dosage used. Salbutamol was found to produce significant increases in minute ventilation, physiological dead space/tidal volume ratio, and ventilatory equivalent for oxygen, with significant falls in arterial oxygen tension and heart rate. Terbutaline did not induce significant changes in any of these variables. These results suggest that terbutaline is less likely than salbutamol to have an adverse effect upon ventilation-perfusion relationships.
摘要
（页码）592 - 595。在14例气道阻塞至少有20%可逆性的患者中，比较了特布他林加压气雾剂给药与沙丁胺醇给药的效果。发现两种药物在所使用的剂量下是等效的支气管扩张剂。发现沙丁胺醇可使分钟通气量、生理无效腔/潮气量比值及氧通气当量显著增加，同时动脉血氧张力和心率显著下降。特布他林在这些变量中均未引起显著变化。这些结果表明，与沙丁胺醇相比，特布他林对通气 - 灌注关系产生不良反应的可能性较小。
相似文献
1
Comparison of cardiorespiratory effects of terbutaline and salbutamol aerosols in patients with reversible airways obstruction.特布他林与沙丁胺醇气雾剂对可逆性气道阻塞患者心肺效应的比较
Thorax. 1973 Sep;28(5):592-5. doi: 10.1136/thx.28.5.592.
2
Comparison of cardiorespiratory effects of rimiterol and terbutaline aerosols.瑞米特罗和特布他林气雾剂对心肺影响的比较。
Bull Physiopathol Respir (Nancy). 1974 Nov-Dec;10(6):801-10.
3
Double-blind trial with increasing doses of salbutamol and terbutaline aerosols in patients with reversible airways obstruction.对可逆性气道阻塞患者使用递增剂量沙丁胺醇和特布他林气雾剂的双盲试验。
Acta Med Scand. 1972 Nov;192(5):371-6. doi: 10.1111/j.0954-6820.1972.tb04832.x.
4
Bronchodilator effect and effect on blood gases after subcutaneous injection and inhalation of terbutaline.
Br J Dis Chest. 1974 Apr;68(2):111-20. doi: 10.1016/0007-0971(74)90023-0.
5
The role of oral bronchodilator therapy as shown by a comparison between salbutamol and terbutaline.
Curr Med Res Opin. 1973;1(9):517-23. doi: 10.1185/03007997309111715.
6
A comparison of salbutamol and terbutaline aerosols in bronchial asthma.沙丁胺醇与特布他林气雾剂治疗支气管哮喘的比较
Practitioner. 1973 Dec;211(266):801-4.
7
Evaluation of a new oral beta2-adrenoceptor stimulant bronchodilator, terbutaline.新型口服β2肾上腺素能兴奋剂支气管扩张剂特布他林的评估
Pharmacology. 1975;13(3):201-11. doi: 10.1159/000136905.
8
9
A comparative trial of salbutamol and isoprenaline in asthma.
Ann Clin Res. 1974 Apr;6(2):126-8.
10
An economical method of comparing inhaled bronchodilators in reversible diffuse airways obstruction. With special reference to a beta-2 stimulant--salmefamol.一种用于比较可逆性弥漫性气道阻塞中吸入性支气管扩张剂的经济方法。特别提及一种β-2兴奋剂——沙美特罗。
Thorax. 1974 May;29(3):317-22. doi: 10.1136/thx.29.3.317.
引用本文的文献
1
Pharmacotherapy of critical asthma syndrome: current and emerging therapies.重症哮喘综合征的药物治疗：当前及新出现的疗法
Clin Rev Allergy Immunol. 2015 Feb;48(1):7-30. doi: 10.1007/s12016-013-8393-8.
2
Comparison of terbutaline and salbutamol inhalation in children with mild or moderate acute exacerbation of asthma.特布他林与沙丁胺醇吸入治疗儿童轻中度哮喘急性加重的比较
Indian J Pediatr. 2004 Nov;71(11):961-3. doi: 10.1007/BF02828104.
3
Haemodynamic effects of terbutaline in chronic obstructive airways disease.特布他林对慢性阻塞性气道疾病的血流动力学影响。
Thorax. 1980 Jul;35(7):536-42. doi: 10.1136/thx.35.7.536.
4
Early effects of intravenous terbutaline on cardiopulmonary function in chronic obstructive bronchitis and pulmonary hypertension.静脉注射特布他林对慢性阻塞性支气管炎和肺动脉高压患者心肺功能的早期影响。
Thorax. 1982 Oct;37(10):746-50. doi: 10.1136/thx.37.10.746.
5
Effect of intravenous terbutaline on arterial blood gas tensions, ventilation, and pulmonary circulation in patients with chronic bronchitis and cor pulmonale.静脉注射特布他林对慢性支气管炎和肺心病患者动脉血气张力、通气及肺循环的影响。
Thorax. 1977 Oct;32(5):601-5. doi: 10.1136/thx.32.5.601.
本文引用的文献
1
SMALL BLOOD-SAMPLES FROM EAR-LOBE PUNCTURE: A SUBSTITUTE FOR ARTERIAL PUNCTURE.耳垂穿刺采集的微量血样：动脉穿刺的替代方法
Lancet. 1965 Aug 14;2(7407):315-7. doi: 10.1016/s0140-6736(65)90286-2.
2
Estimation of arterial CO2 tension by rebreathing technique.通过重复呼吸技术估计动脉血二氧化碳分压。
J Appl Physiol. 1958 May;12(3):425-30. doi: 10.1152/jappl.1958.12.3.425.
3
4
Use of capillary blood in measurement of arterial PO2.毛细血管血在动脉血氧分压测量中的应用。
Br Med J. 1968 Sep 14;3(5619):640-3. doi: 10.1136/bmj.3.5619.640.
5
Comparison of cardiorespiratory effects of isoprenaline and salbutamol in patients with bronchial asthma.支气管哮喘患者中异丙肾上腺素与沙丁胺醇心肺效应的比较。
Br Med J. 1970 Jan 10;1(5688):65-70.
6
Ear lobe blood samples for blood gas analysis at rest and during exercise.
Br J Dis Chest. 1971 Jan;65(1):58-64.
7
Effects of isoprenaline plus phenylephrine by pressurized aerosol on blood gases, ventilation, and perfusion in chronic obstructive lung disease.异丙肾上腺素加去氧肾上腺素加压气雾剂对慢性阻塞性肺疾病患者血气、通气及灌注的影响
Br Med J. 1970 Dec 5;4(5735):579-82. doi: 10.1136/bmj.4.5735.579.
8
Human pharmacological and clinical studies on salbutamol: a specific beta-adrenergic bronchodilator.沙丁胺醇的人体药理学和临床研究：一种特异性β-肾上腺素能支气管扩张剂。
Br J Dis Chest. 1969 Jul;63(3):165-74. doi: 10.1016/s0007-0971(69)80014-8.
9
10
Comparison of two oral selective beta2-adrenergic stimulant drugs in bronchial asthma.两种口服选择性β2肾上腺素能兴奋剂药物在支气管哮喘中的比较。
Br Med J. 1971 Mar 20;1(5750):637-9. doi: 10.1136/bmj.1.5750.637.
Zotero 插件