在给予³H-、⁹⁹ᵐTc-和⁶⁴Cu-博来霉素后，患有内分泌“自主性”乳腺癌大鼠体内放射性物质的相对组织分布。
Relative tissue distribution of radioactivity in rats with endocrine "autonomous" breast carcinomas after 3H-,99mTc-, and 64Cu-bleomycin.
作者信息
Ryo U Y, Ice R D, Jones J D, Beierwaltes W H
出版信息
J Nucl Med. 1975 Feb;16(2):127-31.
PMID:45938
Abstract
The localization of 64Cu-, 3H-, and 99mTc-labeled bleomycin was studied in tissues of Fisher rats bearing an endocrine autonomous breast tumor. The 64Cu-bleomycin showed a greater uptake than 3H- and 99mTc-bleomycin in the breast tumor at all time intervals studied, from 2 to 72 hr after the tracer. This same differential uptake was shared by the liver and kidney.
摘要
研究了64Cu、3H和99mTc标记的博来霉素在患有内分泌自主性乳腺肿瘤的Fisher大鼠组织中的定位情况。在注射示踪剂后的2至72小时内的所有时间间隔，64Cu标记的博来霉素在乳腺肿瘤中的摄取量均高于3H和99mTc标记的博来霉素。肝脏和肾脏也存在同样的摄取差异。
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