[使用57钴、51铬、111铟和99锝标记博来霉素在荷艾氏实体癌小鼠中的分布研究]
[Distribution study using 57Co-, 51Cr-, 111In- and 99mTc-bleomycin in mice with a solid Ehrlich carcinoma].
作者信息
Zimmermann M, Hale T
出版信息
Nuklearmedizin. 1976 Aug;15(4):176-82.
PMID:62345
Abstract
From the comparative studies of 57Co-, 51Cr-, 111In- and 99mTc-Bleomycin using 282 solid Ehrlich-carcinoma-bearing mice, 57Co was found to be the most suitable bleomycin preparation for tumorscintigraphy. The results obtained by 111In-Bleomycin of linear tumor cell absorption indicates a possible use of 111In-Bleomycin as an agent for objective histological differentiation also in cells previously treated with therapeutic agents.
摘要
通过对282只荷艾氏实体癌小鼠使用57钴、51铬、111铟和99m锝标记的博来霉素进行比较研究，发现57钴是肿瘤闪烁显像最适合的博来霉素制剂。111铟标记的博来霉素对肿瘤细胞线性吸收的研究结果表明，111铟标记的博来霉素也有可能作为一种试剂用于对先前接受过治疗药物处理的细胞进行客观的组织学鉴别。
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[Distribution study using 57Co-, 51Cr-, 111In- and 99mTc-bleomycin in mice with a solid Ehrlich carcinoma].[使用57钴、51铬、111铟和99锝标记博来霉素在荷艾氏实体癌小鼠中的分布研究]
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