影响酿酒酵母有性接合及相关过程的突变。II. 非交配突变体的遗传分析。
Mutations affecting sexual conjugation and related processes in Saccharomyces cerevisiae. II. Genetic analysis of nonmating mutants.
作者信息
Mackay V, Manney T R
出版信息
Genetics. 1974 Feb;76(2):273-88. doi: 10.1093/genetics/76.2.273.
Abstract
Rare diploids formed by sterile mutants have been studied by tetrad analysis. Sixteen classes of mutants representing at least five distinct genetic loci have been defined. One group of mutations, isolated only in alpha, maps at the mating-type locus, while none of the others shows any linkage to mating type. Some of the mutations are nonspecific for mating type, while others act only on a or alpha. In addition, mutations were found that prevent sporulation when heterozygous in diploids. These appear to be mutations of the mating-type alleles.
摘要
通过四分体分析对不育突变体形成的稀有二倍体进行了研究。已定义了代表至少五个不同基因座的16类突变体。仅在α中分离出的一组突变位于交配型基因座，而其他突变体均未显示与交配型有任何连锁关系。一些突变对交配型是非特异性的，而另一些仅作用于a或α。此外，还发现了一些突变，当在二倍体中杂合时会阻止孢子形成。这些似乎是交配型等位基因的突变。
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