Borda F, García Carasusan M, Burusco M J, Arin A, Ayensa C, Rivero Puente A
Med Clin (Barc). 1979 Mar 25;72(6):236-8.
One hundred patients with acute pancreatitis are studied. The results in 90 cases were "favorable or very favorable", in ten cases "unfavorable or death". Various different characterisitics were analyzed statistically in relationship to the two types of outcome: sex, clinical histories, and results of physical examination. Furthermore, the individual relationships between age, main initial analytic parameters, and later development were determined. In our experience neither age nor sex, considered individually, showed a significant relationship to the seriousness of the disease. Having had pancreatitis previously proved to be a favorable factor (p less than 0.005). None of the other factors in the case histories showed any bearing of the later course of the condition. Findings in physical examination which were signs of unfavorable prognosis included jaundice (p less than 0.001), low blood pressure (p less than 0.001), tachycardia (p less than 0.005), intestinal paresia (p less than 0.001), pain following decompression (p less than 0.025), and abdominal tenderness (p less than 0.05). Abnormalities in ECG (p less than 0.005), marked leukocytosis (p less than 0.0005), hyperglycemia (p less than 0.02), hypocalcemia (p less than 0.05), and high values for the coefficient of amilase/creatinine clearance (p less than 0.01) also suggested an unfavorable course.
对100例急性胰腺炎患者进行了研究。90例患者的结果为“良好或非常良好”,10例患者的结果为“不良或死亡”。对与这两种结果类型相关的各种不同特征进行了统计分析,包括性别、临床病史和体格检查结果。此外,还确定了年龄、主要初始分析参数与后期病情发展之间的个体关系。根据我们的经验,单独考虑年龄和性别,均未显示与疾病严重程度有显著关系。既往有胰腺炎病史被证明是一个有利因素(p<0.005)。病史中的其他因素均未显示对病情后期发展有任何影响。体格检查中提示预后不良的体征包括黄疸(p<0.001)、低血压(p<0.001)、心动过速(p<0.005)、肠麻痹(p<0.001)、减压后疼痛(p<0.025)和腹部压痛(p<0.05)。心电图异常(p<0.005)、明显白细胞增多(p<0.0005)、高血糖(p<0.02)、低钙血症(p<0.05)以及淀粉酶/肌酐清除率系数高值(p<0.01)也提示病情发展不利。