噬菌体T7诱导的翻译控制
Translational control induced by bacteriophage T7.
作者信息
Herrlich P, Rahmsdorf H J, Pai S H, Schweigher M
出版信息
Proc Natl Acad Sci U S A. 1974 Apr;71(4):1088-92. doi: 10.1073/pnas.71.4.1088.
Abstract
Phage T7 discontinues host gene expression by translational and transcriptional control mechanisms. Translational control is exerted by the T7 translational-repressor. This protein inhibits the synthesis of beta-galactosidase (EC 3.2.1.23) in vivo and in vitro and the synthesis of the T3 enzyme S-adenosylmethioninehydrolase (EC 3.3.1.-). The translational-repressor does not interfere with T7-specific enzyme synthesis. The T7 translational-repressor purifies with the initiation factors. The repressor interacts with the initiation of translation of host enzymes. The translational-repressor gene is close to the promotor for RNA polymerase of Escherichia coli.
摘要
T7噬菌体通过翻译和转录控制机制终止宿主基因表达。翻译控制由T7翻译阻遏物施加。这种蛋白质在体内和体外抑制β-半乳糖苷酶（EC 3.2.1.23）的合成以及T3酶S-腺苷甲硫氨酸水解酶（EC 3.3.1.-）的合成。翻译阻遏物不干扰T7特异性酶的合成。T7翻译阻遏物与起始因子一起纯化。阻遏物与宿主酶翻译的起始相互作用。翻译阻遏物基因靠近大肠杆菌RNA聚合酶的启动子。
相似文献
1
Translational control induced by bacteriophage T7.噬菌体T7诱导的翻译控制
Proc Natl Acad Sci U S A. 1974 Apr;71(4):1088-92. doi: 10.1073/pnas.71.4.1088.
2
Negative control of protein synthesis after infection with bacteriophage T7.噬菌体T7感染后蛋白质合成的负调控
Proc Natl Acad Sci U S A. 1972 Aug;69(8):2203-7. doi: 10.1073/pnas.69.8.2203.
3
DNA-directed enzyme synthesis in vitro.体外DNA指导的酶合成
Curr Top Microbiol Immunol. 1974;65:59-132. doi: 10.1007/978-3-642-65875-4_3.
4
In vivo and in vitro phosphorylation of DNA-dependent RNA polymerase of Escherichia coli by bacteriophage-T7-induced protein kinase.噬菌体T7诱导的蛋白激酶对大肠杆菌依赖DNA的RNA聚合酶的体内和体外磷酸化作用。
Proc Natl Acad Sci U S A. 1975 Jul;72(7):2506-10. doi: 10.1073/pnas.72.7.2506.
5
6
SAMase gene of bacteriophage T3 is responsible for overcoming host restriction.噬菌体T3的SAMase基因负责克服宿主限制。
J Virol. 1976 Jul;19(1):136-45. doi: 10.1128/JVI.19.1.136-145.1976.
7
Synthesis of bacteriophage-coded gene products during infection of Escherichia coli with amber mutants of T3 and T7 defective in gene 1.用T3和T7基因1有缺陷的琥珀突变体感染大肠杆菌期间噬菌体编码基因产物的合成。
J Virol. 1973 Apr;11(4):465-72. doi: 10.1128/JVI.11.4.465-472.1973.
8
Initiation of transcription by RNA polymerases of E. coli and phage T3.大肠杆菌和噬菌体T3的RNA聚合酶引发转录
Adv Exp Med Biol. 1974 Jun;44(1):7-21. doi: 10.1007/978-1-4684-3246-6_2.
9
Control of gene expression in bacteriophage T7. Isolation of a new control protein and mechanism of action.噬菌体T7中的基因表达调控。一种新调控蛋白的分离及其作用机制。
Mol Gen Genet. 1974;134(1):29-38. doi: 10.1007/BF00332810.
10
Cleavage by RNase 3 converts T3 and T7 early precursor RNA into translatable message.核糖核酸酶3的切割作用将T3和T7早期前体RNA转化为可翻译的信使RNA。
Proc Natl Acad Sci U S A. 1974 Mar;71(3):840-4. doi: 10.1073/pnas.71.3.840.
引用本文的文献
1
A Grad-seq View of RNA and Protein Complexes in Pseudomonas aeruginosa under Standard and Bacteriophage Predation Conditions.在标准条件和噬菌体捕食条件下铜绿假单胞菌中 RNA 和蛋白质复合物的 Grad-seq 观察。
mBio. 2021 Feb 9;12(1):e03454-20. doi: 10.1128/mBio.03454-20.
2
Protein phosphatase 2A (PP2A)-specific ubiquitin ligase MID1 is a sequence-dependent regulator of translation efficiency controlling 3-phosphoinositide-dependent protein kinase-1 (PDPK-1).蛋白磷酸酶 2A（PP2A）特异性泛素连接酶 MID1 是一种依赖于序列的翻译效率调节剂，可调控 3-磷酸肌醇依赖性蛋白激酶-1（PDPK-1）。
J Biol Chem. 2011 Nov 18;286(46):39945-57. doi: 10.1074/jbc.M111.224451. Epub 2011 Sep 19.
3
Repair rate in human fibroblasts measured by thymine dimer excorporation.通过胸腺嘧啶二聚体切除法测定人成纤维细胞的修复率。
Mol Gen Genet. 1982;188(2):309-12. doi: 10.1007/BF00332693.
4
Bacteriophage T3 and bacteriophage T7 virus-host cell interactions.噬菌体T3与噬菌体T7的病毒-宿主细胞相互作用。
Microbiol Rev. 1981 Mar;45(1):9-51. doi: 10.1128/mr.45.1.9-51.1981.
5
Control of gene expression in bacteriophage T7. Isolation of a new control protein and mechanism of action.噬菌体T7中的基因表达调控。一种新调控蛋白的分离及其作用机制。
Mol Gen Genet. 1974;134(1):29-38. doi: 10.1007/BF00332810.
6
Control of gene expression in bacteriophage T7: transcriptional controls.噬菌体T7中的基因表达调控：转录调控
Mol Gen Genet. 1974;134(4):281-97. doi: 10.1007/BF00337463.
7
Early gene expression in bacteriophage T7. I. In vivo synthesis, inactivation, and translational utilization of early mRNA's.噬菌体T7中的早期基因表达。I. 早期信使核糖核酸的体内合成、失活及翻译利用
J Virol. 1976 Feb;17(2):642-58. doi: 10.1128/JVI.17.2.642-658.1976.
8
E. coli membranes become permeable to ions following T7-virus-infection.在受到T7病毒感染后，大肠杆菌细胞膜对离子的通透性会增加。
Mol Gen Genet. 1976 Dec 8;149(2):145-50. doi: 10.1007/BF00332882.
9
Early T7 gene expression: rates of RNA synthesis and degradation, protein kinase dependent termination of transcription, and efficiency of translation.早期T7基因表达：RNA合成与降解速率、蛋白激酶依赖性转录终止以及翻译效率。
Mol Gen Genet. 1978 Oct 30;166(2):127-40. doi: 10.1007/BF00285915.
10
Radiation sensitivity of messenger RNA.信使核糖核酸的辐射敏感性
Mol Gen Genet. 1979 Aug;175(1):13-7. doi: 10.1007/BF00267850.
本文引用的文献
1
RESTORATION OF OPERON ACTIVITY BY SUPPRESSORS.通过抑制子恢复操纵子活性
Biochim Biophys Acta. 1963 Sep 17;76:162-4.
2
Deficiency in initiation factors of protein synthesis induced by phage T7 in E. coli F(+) strains.噬菌体T7在大肠杆菌F(+)菌株中诱导的蛋白质合成起始因子缺乏。
FEBS Lett. 1972 Oct 15;27(1):1-4. doi: 10.1016/0014-5793(72)80394-6.
3
The effects of ultraviolet irradiation on the transcription of T4 DNA.紫外线照射对T4 DNA转录的影响。
Biochim Biophys Acta. 1970;209(2):368-86. doi: 10.1016/0005-2787(70)90735-5.
4
Gene expression in vitro from deoxyribonucleic acid of bacteriophage T7.噬菌体T7脱氧核糖核酸的体外基因表达
J Biol Chem. 1971 Nov 25;246(22):6707-12.
5
New RNA polymerase from Escherichia coli infected with bacteriophage T7.来自被噬菌体T7感染的大肠杆菌的新型RNA聚合酶。
Nature. 1970 Oct 17;228(5268):227-31. doi: 10.1038/228227a0.
6
Dynamics of synthesis, translation, and degradation of trp operon messenger RNA in E. coli.大肠杆菌中色氨酸操纵子信使核糖核酸的合成、翻译及降解动力学
Cold Spring Harb Symp Quant Biol. 1969;34:725-40. doi: 10.1101/sqb.1969.034.01.082.
7
The genetics and physiology of bacteriophage T7.噬菌体T7的遗传学与生理学
Virology. 1969 Nov;39(3):562-74. doi: 10.1016/0042-6822(69)90104-4.
8
Ribosomes after infection with bacteriophage T4 and T7.感染噬菌体T4和T7后的核糖体。
Mol Gen Genet. 1973 Dec 31;127(3):259-71. doi: 10.1007/BF00333766.
9
Physical mapping of the early region of bacteriophage T7 DNA.噬菌体T7 DNA早期区域的物理图谱
J Mol Biol. 1973 Sep 15;79(2):249-65. doi: 10.1016/0022-2836(73)90004-1.
10
The process of infection with coliphage 17. VI. A phage gene controlling shutoff of host RNA synthesis.大肠杆菌噬菌体17的感染过程。第六章。一个控制宿主RNA合成关闭的噬菌体基因。
Virology. 1972 Nov;50(2):322-7. doi: 10.1016/0042-6822(72)90383-2.
Zotero 插件