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灰黄霉素对二倍体构巢曲霉有丝分裂时染色体分离的干扰作用。

Interference of griseofulvin with the segregation of chromosomes at mitosis in diploid Aspergillus nidulans.

作者信息

Kappas A, Georgopoulos S G

出版信息

J Bacteriol. 1974 Jul;119(1):334-5. doi: 10.1128/jb.119.1.334-335.1974.

Abstract

Low concentrations of the antibiotic griseofulvin were found to cause increased frequencies of somatic segregation due to chromosome nondisjunction in a diploid strain of Aspergillus nidulans.

摘要

在构巢曲霉的一个二倍体菌株中,发现低浓度的抗生素灰黄霉素会因染色体不分离导致体细胞分离频率增加。

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本文引用的文献

1
The processes of spontaneous recombination in vegetative nuclei of Aspergillus nidulans.
Genetics. 1961 Dec;46(12):1581-609. doi: 10.1093/genetics/46.12.1581.
2
Mutational resistance to fungitoxic benzimidazole derivatives in Aspergillus nidulans.
J Gen Microbiol. 1971 Aug;67(3):371-3. doi: 10.1099/00221287-67-3-371.
3
On the genetic activity of benzimidazole and thiophanate fungicides on diploid Aspergillus nidulans.
Mutat Res. 1974 Feb;26(1):17-27. doi: 10.1016/s0027-5107(74)80066-7.
4
The effects of griseofulvin on mitosis in Aspergillus nidulans.
Can J Microbiol. 1972 May;18(5):683-7. doi: 10.1139/m72-106.

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