Roberts G D, Larsh H W
Infect Immun. 1974 Jul;10(1):30-3. doi: 10.1128/iai.10.1.30-33.1974.
Immunocytoadherence was investigated as a method of detecting active histoplasmosis in two groups of infected New Zealand white rabbits. Yeast-phase Histoplasma capsulatum was given intravenously to one group and intratracheally to the other. There was a striking correlation between the clinical condition of the animals and the number of rosettes seen. This number increased as the infection progressed and decreased as it regressed. The immunocytoadherence technique might be of value in detecting active histoplasmosis, and investigation in humans is warranted.
对两组感染的新西兰白兔，研究了免疫细胞黏附作为检测活动性组织胞浆菌病的一种方法。将酵母相荚膜组织胞浆菌静脉注射给一组，气管内注射给另一组。动物的临床状况与观察到的玫瑰花环数量之间存在显著相关性。随着感染进展，这个数量增加；随着感染消退，这个数量减少。免疫细胞黏附技术在检测活动性组织胞浆菌病方面可能有价值，有必要在人类中进行研究。
