Rantala M, Nurmi E
J Hyg (Lond). 1974 Jun;72(3):349-54. doi: 10.1017/s0022172400023573.
The purpose of this work was to study the effects of interrupted, continuous and post-salmonella inoculation treatment with furazolidone in the feed on the colonization of Salmonella infantis in the intestines of chickens, as well as the influence of furazolidone in vitro on the effect of a mixed culture used for the prevention of salmonellosis in chickens.It was shown that chickens given interrupted treatment with 0.01% furazolidone had significantly more salmonellas in the caeca than either chickens fed continuously with this drug or chickens without any treatment. The use of 0.01% furazolidone after inoculation with Salmonella infantis had no effect on Salmonella infantis in the caeca of chickens.The mixed bacterial culture from the normal intestinal flora lost its preventive effect on salmonellosis when cultured with 0.01% furazolidone.
本研究旨在探讨饲料中添加呋喃唑酮进行间断、连续及沙门氏菌接种后处理对鸡肠道中婴儿沙门氏菌定植的影响,以及呋喃唑酮体外对用于预防鸡沙门氏菌病的混合培养物效果的影响。结果表明,用0.01%呋喃唑酮进行间断处理的鸡盲肠中的沙门氏菌明显多于持续投喂该药物的鸡或未进行任何处理的鸡。接种婴儿沙门氏菌后使用0.01%呋喃唑酮对鸡盲肠中的婴儿沙门氏菌没有影响。当与0.01%呋喃唑酮一起培养时,来自正常肠道菌群的混合细菌培养物失去了对沙门氏菌病的预防作用。