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Dependence of specific metabolism of benzo(a)pyrene on the inducer of hydroxylase activity.

作者信息

Rasmussen R E, Wang I Y

出版信息

Cancer Res. 1974 Sep;34(9):2290-5.

PMID:4602111
Abstract
摘要

相似文献

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Dependence of specific metabolism of benzo(a)pyrene on the inducer of hydroxylase activity.苯并(a)芘的特定代谢对羟化酶活性诱导剂的依赖性。
Cancer Res. 1974 Sep;34(9):2290-5.
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Quantitative relationship between carcinogenicity and mutagenicity of polyaromatic hydrocarbons in Salmonella typhimurium mutants.鼠伤寒沙门氏菌突变体中多环芳烃致癌性与致突变性的定量关系。
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Effect of enzyme induction on the metabolism and tissue distribution of benzo(alpha)pyrene.酶诱导对苯并(α)芘代谢及组织分布的影响。
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Proceedings: Influence of epoxide hydrase inhibitors on mutagenic effects of reactive metabolites generated in situ from benzo(a)pyrene.会议论文:环氧水解酶抑制剂对苯并(a)芘原位生成的活性代谢产物致突变作用的影响
Naunyn Schmiedebergs Arch Pharmacol. 1974;282(Suppl):suppl 282:R24.
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Mutagenicity of non-K-region diols and diol-epoxides of benz(a)anthracene and benzo(a)pyrene in S. typhimurium TA 100.苯并(a)蒽和苯并(a)芘的非K区域二醇及二醇环氧化物在鼠伤寒沙门氏菌TA 100中的诱变性。
Biochem Biophys Res Commun. 1975 Sep 16;66(2):693-700. doi: 10.1016/0006-291x(75)90565-3.
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Induction and repression of microsomal drug-metabolizing enzymes by polycyclic hydrocarbons and phenobarbital: theoretical models.
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Mutagenesis of certain activated carcinogens in vitro associated with genetically mediated increases in monooxygenase activity and cytochrome P 1-450.某些体外活化致癌物的诱变作用与单加氧酶活性和细胞色素P 1-450的遗传介导性增加有关。
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K-region epoxides of polycyclic hydrocarbons: formation and further metabolism by rat-lung preparations.
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Metabolic activation of aromatic hydrocarbons in purified rat liver nuclei: induction of enzyme activities and binding to DNA with and without monooxygenase-catalyzed formation of active oxygen.纯化大鼠肝细胞核中芳烃的代谢激活:酶活性的诱导以及在有无单加氧酶催化活性氧形成情况下与DNA的结合。
Proc Natl Acad Sci U S A. 1976 Feb;73(2):457-61. doi: 10.1073/pnas.73.2.457.

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Relationship between biotransformation and the toxicity and fate of xenobiotic chemicals in fish.鱼类体内生物转化与外源化学物质的毒性及归宿之间的关系。
Environ Health Perspect. 1980 Feb;34:115-31. doi: 10.1289/ehp.8034115.
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Determination of cytochrome P-448 activity in biological tissues.生物组织中细胞色素P-448活性的测定。
Biochem J. 1984 Jul 1;221(1):81-8. doi: 10.1042/bj2210081.
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Aryl and aniline hydroxylases in rat nuclear membranes after pretreatment with pregnenolone 16alpha-carbonitrile, phenobarbital and methylcholanthrene.
经孕烯醇酮16α-腈、苯巴比妥和甲基胆蒽预处理后大鼠核膜中的芳基和苯胺羟化酶
Experientia. 1975 Jul 15;31(7):778-9. doi: 10.1007/BF01938459.
4
Mutagenic and cytotoxic activity of benzol[a]pyrene 4,5-, 7,8-, and 9,10-oxides and the six corresponding phenols.苯并[a]芘4,5-、7,8-和9,10-氧化物以及六种相应酚类的致突变和细胞毒性活性。
Proc Natl Acad Sci U S A. 1975 Aug;72(8):3176-80. doi: 10.1073/pnas.72.8.3176.
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Position-specific oxygenation of benzo(a)pyrene by different forms of purified cytochrome P-450 from rabbit liver.兔肝中不同形式的纯化细胞色素P-450对苯并(a)芘的位点特异性氧化作用。
Proc Natl Acad Sci U S A. 1975 Oct;72(10):3917-20. doi: 10.1073/pnas.72.10.3917.
6
Genetic aspects of toxicity during development.发育过程中毒性的遗传学方面。
Environ Health Perspect. 1976 Dec;18:35-45. doi: 10.1289/ehp.761835.
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Species differences in activating and inactivating enzymes related to the control of mutagenic metabolites.与诱变代谢物控制相关的激活和失活酶的物种差异。
Arch Toxicol. 1977 Dec 30;39(1-2):97-108. doi: 10.1007/BF00343279.