恒化器中高突变率的选择。
Selection for high mutation rates in chemostats.
作者信息
Cox E C, Gibson T C
出版信息
Genetics. 1974 Jun;77(2):169-84. doi: 10.1093/genetics/77.2.169.
Abstract
Competition experiments in chemostats show that mutator populations of Escherichia coli are more fit than wild type. The increased fitness can be explained by the appearance of new mutants better adapted to the chemostat environment. Fitness values vary between chemostats and are strongly correlated (P < 0.001) with fluctuations in population density.
摘要
恒化器中的竞争实验表明，大肠杆菌的突变体群体比野生型更具适应性。适应性的提高可以通过出现更适应恒化器环境的新突变体来解释。不同恒化器中的适应性值各不相同，并且与种群密度的波动密切相关（P < 0.001）。
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本文引用的文献
1
Segregation of the Selective Advantage Obtained through Orthoselection in Escherichia Coli.大肠杆菌中通过定向选择获得的选择优势的分离
Genetics. 1955 Nov;40(6):937-50. doi: 10.1093/genetics/40.6.937.
2
Theory of fitness in a heterogeneous environment. VI. The adaptive significance of mutation.异质环境中的适合度理论。VI. 突变的适应性意义。
Genetics. 1967 May;56(1):163-78. doi: 10.1093/genetics/56.1.163.
3
A proposal for a uniform nomenclature in bacterial genetics.细菌遗传学统一命名法的提议。
Genetics. 1966 Jul;54(1):61-76. doi: 10.1093/genetics/54.1.61.
4
The genetics of a mutator gene in Drosophila melanogaster.黑腹果蝇中一个诱变基因的遗传学
Mutat Res. 1970 Oct;10(4):353-63. doi: 10.1016/0027-5107(70)90048-5.
5
Genetic analysis of sul mutants of Escherichia coli B.大肠杆菌B株sul突变体的遗传分析。
Genet Res. 1971 Jun;17(3):185-93. doi: 10.1017/s0016672300012210.
6
Fitness of an Escherichia coli mutator gene.大肠杆菌突变基因的适应性
Science. 1970 Aug 14;169(3946):686-8. doi: 10.1126/science.169.3946.686.
7
Altered base ratios in the DNA of an Escherichia coli mutator strain.大肠杆菌突变菌株DNA中碱基比率的改变。
Proc Natl Acad Sci U S A. 1967 Nov;58(5):1895-902. doi: 10.1073/pnas.58.5.1895.
8
In vitro characterization of a mutator T4 DNA polymerase.突变型T4 DNA聚合酶的体外特性研究
Genetics. 1973 Apr;73:Suppl 73:131-6.
9
Population changes in continuously growing mutator cultures of Escherichia coli.大肠杆菌持续生长的突变体培养物中的种群变化。
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Mutator gene studies in Escherichia coli: the mutS gene.大肠杆菌中的突变基因研究：mutS基因
Genetics. 1972 Dec;72(4):551-67. doi: 10.1093/genetics/72.4.551.
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