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Light-activated drug confirms a mechanism of ion channel blockade.

作者信息

Lester H A, Krouse M E, Nass M M, Wassermann N H, Erlanger B F

出版信息

Nature. 1979 Aug 9;280(5722):509-10. doi: 10.1038/280509a0.

DOI:10.1038/280509a0
PMID:460432
Abstract
摘要

相似文献

1
Light-activated drug confirms a mechanism of ion channel blockade.光激活药物证实了离子通道阻断机制。
Nature. 1979 Aug 9;280(5722):509-10. doi: 10.1038/280509a0.
2
Electrophysiological experiments with photoisomerizable cholinergic compounds: review and progress report.使用光异构化胆碱能化合物的电生理实验：综述与进展报告
Ann N Y Acad Sci. 1980;346:475-90. doi: 10.1111/j.1749-6632.1980.tb22118.x.
3
The sodium channel from Electrophorus electricus.电鳗的钠通道。
Ann N Y Acad Sci. 1986;479:162-78. doi: 10.1111/j.1749-6632.1986.tb15568.x.
4
A covalently bound photoisomerizable agonist: comparison with reversibly bound agonists at Electrophorus electroplaques.一种共价结合的光异构化激动剂：与电鳐电板上可逆结合的激动剂的比较。
J Gen Physiol. 1980 Feb;75(2):207-32. doi: 10.1085/jgp.75.2.207.
5
Binding of Naja nigricollis (3H)alpha-toxin to membrane fragments from Electrophorus and Torpedo electric organs. II. Effect of cholinergic agonists and antagonists on the binding of the tritiated alpha-neurotoxin.眼镜蛇（3H）α-毒素与电鳗和电鳐电器官膜片段的结合。II. 胆碱能激动剂和拮抗剂对氚化α-神经毒素结合的影响。
Mol Pharmacol. 1974 Jan;10(1):15-34.
6
Response of acetylcholine receptors to rapid photochemically produced increases in agonist concentration.乙酰胆碱受体对光化学快速产生的激动剂浓度增加的反应。
Nature. 1977 Mar 24;266(5600):373-4. doi: 10.1038/266373a0.
7
Microelectrophoretic application of cholinergic compounds, protein oxidizing agents, and mercurials to the chemically excitable membrane of the electroplax.
Proc Natl Acad Sci U S A. 1972 Aug;69(8):2081-5. doi: 10.1073/pnas.69.8.2081.
8
Effect of histrionicotoxin on ion channels in synaptic and conducting membranes of electroplax of Electrophorus electricus.组织毒素对电鳗电板突触膜和传导膜中离子通道的影响。
Cell Mol Neurobiol. 1983 Sep;3(3):203-12. doi: 10.1007/BF00710947.
9
Analysis of sodium and potassium redistribution during sustained permeability increases at the innervated face of Electrophorus electroplaques.电鳐电板受神经支配面持续通透性增加期间钠和钾再分布的分析
J Gen Physiol. 1978 Dec;72(6):847-62. doi: 10.1085/jgp.72.6.847.
10
Competitive block and ion channel block as mechanisms of antagonist action on the skeletal muscle end-plate.竞争性阻断和离子通道阻断作为拮抗剂作用于骨骼肌终板的机制。
Adv Biochem Psychopharmacol. 1980;21:67-80.

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Nat Rev Neurosci. 2019 Sep;20(9):514-532. doi: 10.1038/s41583-019-0197-2.
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Front Synaptic Neurosci. 2019 Jan 9;10:48. doi: 10.3389/fnsyn.2018.00048. eCollection 2018.
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Synapses in the spotlight with synthetic optogenetics.合成光遗传学聚焦突触
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