普萘洛尔治疗偏头痛
Propranolol in the treatment of migraine.
作者信息
Wideroe T E, Vigander T
出版信息
Br Med J. 1974 Jun 29;2(5921):699-701. doi: 10.1136/bmj.2.5921.699.
Abstract
Beta-blocking drugs that prevent cranial vasodilatation are potentially valuable in the prophylaxis of migraine. Forty-nine patients with either classic or common migraine were treated with propranolol 160 mg/day for an average of six months. The first 30 of the patients to respond well to this treatment then participated in a double-blind cross-over trial with a placebo and propranolol. The mean frequency of headache attacks was significantly reduced by propranolol. None of the patients expressed a preference for placebo. Propranolol seems to be an effective prophylactic for common and classic migraine but the antimigraine properties of the various beta-blocking agents probably differ.
摘要
可预防颅血管扩张的β受体阻滞剂在偏头痛预防方面可能具有重要价值。49例典型或普通偏头痛患者接受了每日160毫克普萘洛尔治疗，平均治疗时间为6个月。最初对该治疗反应良好的30例患者随后参与了一项安慰剂与普萘洛尔的双盲交叉试验。普萘洛尔显著降低了头痛发作的平均频率。没有患者表示更喜欢安慰剂。普萘洛尔似乎是普通偏头痛和典型偏头痛的有效预防药物，但各种β受体阻滞剂的抗偏头痛特性可能有所不同。
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本文引用的文献
1
The treatment of angina pectoris with coexistent migraine.合并偏头痛的心绞痛的治疗
Practitioner. 1968 May;200(199):702-4.
2
In vivo observations of the microcirculation of the bulbar conjunctiva in migraneous.对球结膜微循环进行体内动态观察。
Res Clin Stud Headache. 1970;3:277-93.
3
The prophylactic value of propranolol in angina pectoris.
Am J Cardiol. 1966 Sep;18(3):370-83. doi: 10.1016/0002-9149(66)90056-7.
4
Propranolol prophylaxis of migraine.普萘洛尔预防偏头痛。
Headache. 1973 Jan;12(4):163-7. doi: 10.1111/j.1526-4610.1973.hed1204163.x.
5
Clinical trial of LB-46 (d, 1-4-(2-hydroxy-3-isopropylaminopropoxy)indol. An adrenergic beta-receptor blocking agent in migraine prophylaxis.LB - 46（d，1 - 4 -（2 - 羟基 - 3 - 异丙氨基丙氧基）吲哚）的临床试验。一种用于偏头痛预防的肾上腺素能β受体阻滞剂。
Headache. 1972 Apr;12(1):15-7. doi: 10.1111/j.1526-4610.1972.hed1201015.x.
6
Clinical trial of a beta-receptor blocking agent (LB 46) in migraine prophylaxis.一种β受体阻滞剂（LB 46）用于偏头痛预防的临床试验。
Acta Neurol Scand. 1972;48(1):124-8. doi: 10.1111/j.1600-0404.1972.tb07532.x.
7
[Effect of beta-adrenergic blockaders in bronchial asthma].[β-肾上腺素能阻滞剂在支气管哮喘中的作用]
Med Klin. 1971 Dec 24;66(52):1804-7.
8
Treatment of migraine with propranolol.用普萘洛尔治疗偏头痛。
Lancet. 1968 Nov 2;2(7575):980. doi: 10.1016/s0140-6736(68)91219-1.
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