Wilkinson H A, Schuman N
Neurosurgery. 1979 May;4(5):401-9. doi: 10.1227/00006123-197905000-00005.
From a series of 681 patients with lumbar disc disease treated between 1966 and 1978, 17 patients required surgical lysis of lumbar adhesive arachnoiditis, 8 having initially been operated upon by another surgeon. All patients had severe pain as a predominant feature, with pain being bilateral in 9 patients. Pain was the only major symptom in 3; the other 14 exhibited varying combinations of progressive neurological dysfunction. Three patients developed late symptoms after trauma, 8 to 21 years after back surgery. At operation, multisegmental arachnoiditis was found in 5 patients and anular or subtotal adhesions were found in 12. Complete lysis could not be obtained in 4 patients. Fourteen patients were treated with steroids at the time of operation. Follow-up after lysis was less than 1 year for 5 patients but averaged 4.8 years for the remaining 12. During the 1st year after operation, 76% experienced improvement in pain (35%, good to excellent), 71% experienced improvement in neurological status. Follow-up after at least 1 year revealed 50% still enjoying pain relief (25%, good to excellent) and 45% experiencing neurological improvement. Pain relief persisted in 4 of 5 patients followed 5 years or more. The etiological role of myelograpy and lumbar disc surgery in arachnoiditis has probably been over-rated. Arachnoiditis may be symptomatic or asymptomatic and may mask other, treatable lumbar lesions. More frequent intradural exploration for discrepancies between operative and myelographic findings might reveal, and benefit, more cases of spontaneous arachnoiditis mimicking lumbar disc disease.
在1966年至1978年间接受治疗的681例腰椎间盘疾病患者中,有17例需要进行腰椎粘连性蛛网膜炎的手术松解,其中8例最初由其他外科医生进行过手术。所有患者均以严重疼痛为主要特征,9例患者疼痛为双侧性。3例患者疼痛是唯一的主要症状;其他14例表现出不同程度的进行性神经功能障碍组合。3例患者在创伤后出现晚期症状,发生于背部手术后8至21年。手术时,5例患者发现多节段蛛网膜炎,12例发现环状或部分粘连。4例患者无法实现完全松解。14例患者在手术时接受了类固醇治疗。5例患者松解术后随访时间不足1年,其余12例平均随访4.8年。术后第1年,76%的患者疼痛得到改善(35%为良好至优秀),71%的患者神经功能状态得到改善。至少随访1年后发现,50%的患者仍有疼痛缓解(25%为良好至优秀),45%的患者神经功能得到改善。随访5年或更长时间的5例患者中有4例疼痛持续缓解。脊髓造影和腰椎间盘手术在蛛网膜炎中的病因学作用可能被高估了。蛛网膜炎可能有症状或无症状,可能掩盖其他可治疗的腰椎病变。对于手术和脊髓造影结果之间的差异,更频繁地进行硬膜内探查可能会发现更多类似腰椎间盘疾病的自发性蛛网膜炎病例,并使其受益。