甘氨酸对大鼠皮层神经元的抑制作用。

The inhibitory action of glycine on rat cortical neurons.

作者信息

Bernardi G, Cherubini E, Marciani M G, Stanzione P

出版信息

Neurosci Lett. 1979 May;12(2-3):335-8. doi: 10.1016/0304-3940(79)96085-3.

Abstract

The action of glycine (Gly) on rat cortical neurons was studied. Gly, iontophoretically applied, hyperpolarized the membrane potential, blocked the firing rate and decreased the amplitude of EPSP-IPSP sequences. Generally the membrane resistance during the aminoacid ejection decreased. The role of Gly in the rat cortical inhibition is discussed.

摘要

研究了甘氨酸（Gly）对大鼠皮层神经元的作用。通过离子电泳施加的甘氨酸使膜电位超极化，阻断放电频率并降低兴奋性突触后电位-抑制性突触后电位序列的幅度。一般来说，在氨基酸喷射期间膜电阻降低。讨论了甘氨酸在大鼠皮层抑制中的作用。