γ-氨基丁酸（GABA）和甘氨酸对大鼠皮层神经元的作用机制。

Action mechanisms of gamma-aminobutyric acid (GABA) and glycine on rat cortical neurons.

作者信息

Marciani M G, Stanzione P, Cherubini E, Bernardi G

出版信息

Neurosci Lett. 1980 Jun;18(2):169-72. doi: 10.1016/0304-3940(80)90321-3.

Abstract

The actions of GABA and glycine (Gly), iontophoretically applied to rat cortical neurons, were compared. These amino acids hyperpolarized the membrane cell, decreasing the membrane resistance. The results show that the ionic mechanisms involved in the inhibitory actions of GABA and Gly are probably the same in contrast with the results obtained in cat cortical neurons.

摘要

对通过离子电渗法施加于大鼠皮层神经元的γ-氨基丁酸（GABA）和甘氨酸（Gly）的作用进行了比较。这些氨基酸使细胞膜超极化，降低了膜电阻。结果表明，与在猫皮层神经元中获得的结果相反，GABA和Gly抑制作用所涉及的离子机制可能是相同的。