Baggs W J, Amor R L
Obstet Gynecol. 1979 Aug;54(2):156-62.
In the course of their practice 2 gynecologists have conducted a program of screening for breast cancer in 1538 patients ages 35-49 years and on 1102 patients ages 50 or older. The screening protocol of breast examinations, thermography, and selective mammography is described. Twenty-four (9/1000) breast cancers were found, 12 in each age group. Eight of these (3/1000) were clinically occult (6 in the younger age group, 4/1000) and were detected by abnormal thermograms followed by mammography. Of the 12 cancers in the 35-49-year-old age group, 6 were discovered at the first screening, and the other 6 by thermographic changes at intervals of 6-24 months. Thermographic screening is more accurate than breast examination alone, but less accurate than if mammography is included. However, since routine annual use of the latter in younger women still raises concerns about x-ray dosage, thermography is a valuable adjunct to physical examination alone. When it is abnormal, mammography is indicated. The 3 complementary methods can reveal about 9 of 10 preclinical cancers in young women.
在其执业过程中,2名妇科医生对1538名35至49岁的患者以及1102名50岁及以上的患者开展了一项乳腺癌筛查项目。文中描述了乳房检查、热成像和选择性乳房X光造影的筛查方案。共发现24例(9/1000)乳腺癌,每个年龄组各12例。其中8例(3/1000)为临床隐匿性癌症(较年轻年龄组6例,4/1000),通过异常热成像图随后进行乳房X光造影检测到。在35至49岁年龄组的12例癌症中,6例在首次筛查时发现,另外6例通过6至24个月间隔期的热成像变化发现。热成像筛查比单纯乳房检查更准确,但比包含乳房X光造影时准确性低。然而,由于在年轻女性中每年常规使用后者仍引发对X射线剂量的担忧,热成像仍是单纯体格检查的一项有价值的辅助手段。当热成像异常时,需进行乳房X光造影。这三种互补方法可发现年轻女性中约十分之九的临床前癌症。