低出生体重儿中的叶酸
Folic acid in low birthweight infants.
作者信息
Kendall A C, Jones E E, Wilson C I, Shinton N K, Elwood P C
出版信息
Arch Dis Child. 1974 Sep;49(9):736-8. doi: 10.1136/adc.49.9.736.
Abstract
A double-blind randomized trial of 50 μg folic acid or placebo given from 2 weeks to 6 months to 130 infants of birthweight less than 2·5 kg has been conducted. While only 62 of the babies completed the 6-month follow-up, no significant difference was found between either group in respect of changes in weight, haemoglobin, serum folate, red cell folate, or evidence of infection. It is concluded that infants in this series were receiving adequate amounts of folic acid in their normal diet and did not require supplements.
摘要
对130名出生体重低于2.5千克的婴儿进行了一项双盲随机试验，从出生后2周开始至6个月，分别给予50微克叶酸或安慰剂。虽然只有62名婴儿完成了6个月的随访，但两组在体重、血红蛋白、血清叶酸、红细胞叶酸或感染迹象的变化方面均未发现显著差异。得出的结论是，该系列中的婴儿在正常饮食中已摄入足够量的叶酸，无需补充。
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本文引用的文献
1
Megaloblastic anaemias.巨幼细胞贫血
Pediatr Clin North Am. 1962 Aug;9:727-38.
2
Folate state of premature infants.早产儿的叶酸状态
Arch Dis Child. 1969 Oct;44(237):637-42. doi: 10.1136/adc.44.237.637.
3
Response of low birthweight infant to treatment with folic acid.低体重婴儿对叶酸治疗的反应。
Arch Dis Child. 1971 Apr;46(246):189-94. doi: 10.1136/adc.46.246.189.
4
Effect of folic acid treatment on premature infants.叶酸治疗对早产儿的影响。
Arch Dis Child. 1972 Aug;47(254):631-4. doi: 10.1136/adc.47.254.631.
5
Folate deficiency in premature infants.早产儿的叶酸缺乏
Arch Dis Child. 1970 Aug;45(242):441-4. doi: 10.1136/adc.45.242.441.
6
Response to oral administration of pteroylmonoglutamic acid or pteroylpolyglutamate in newborn infants of low birth weight.低体重新生儿口服蝶酰单谷氨酸或蝶酰多谷氨酸后的反应
Br J Nutr. 1973 Sep;30(2):165-9. doi: 10.1079/bjn19730021.
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