内毒素耐受性以及小鼠对都柏林沙门氏菌和无乳链球菌感染的非特异性抗性诱导
Endotoxin tolerance and the induction of nonspecific resistance to Salmonella dublin and Streptococcus agalactiae infections in mice.
作者信息
Hill A W, Hibbitt K G, Shears A
出版信息
Br J Exp Pathol. 1974 Jun;55(3):269-74.
Abstract
Data are presented in this paper which show that endotoxin stimulated nonspecific resistance of mice to bacterial infections is not lost when the animals become tolerant to endotoxin and in some cases can be increased as the animals become more tolerant to endotoxin. Experiments are also presented which suggest that the specific antibodies to endotoxin that develop in the serum of tolerant animals may be unimportant in the development of the tolerance or in the enhancement of the nonspecific resistance.
摘要
本文所呈现的数据表明，当动物对内毒素产生耐受时，内毒素刺激的小鼠对细菌感染的非特异性抵抗力不会丧失，并且在某些情况下，随着动物对内毒素的耐受性增强，这种抵抗力还会增加。文中还展示了一些实验，这些实验表明，耐受动物血清中产生的内毒素特异性抗体，在耐受性的形成或非特异性抵抗力的增强过程中可能并不重要。
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引用本文的文献
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本文引用的文献
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Studies with radioactive endotoxin. I. The use of Cr51 to label endotoxin of Escherichia coli.放射性内毒素研究。I. 利用铬51标记大肠杆菌内毒素
J Clin Invest. 1955 Jun;34(6):850-7. doi: 10.1172/JCI103140.
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QUANTITATIVE STUDIES OF FEBRILE TOLERANCE AND LEVELS OF SPECIFIC ANTIBODY EVOKED BY BACTERIAL ENDOTOXIN.细菌内毒素引起的发热耐受性及特异性抗体水平的定量研究。
J Clin Invest. 1965 Jun;44(6):920-8. doi: 10.1172/JCI105209.
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RELATIONSHIP OF ENDOGENOUS PYROGEN AND SERUM AUGMENTING FACTOR TO ENDOTOXIN TOLERANCE.内源性致热原和血清增强因子与内毒素耐受性的关系。
Proc Soc Exp Biol Med. 1965 May;119:218-21. doi: 10.3181/00379727-119-30141.
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Mechanisms of endotoxin tolerance. I. Relationship between tolerance and reticuloendothelial system phagocytic activity in the rabbit.内毒素耐受的机制。I. 兔体内耐受与网状内皮系统吞噬活性之间的关系。
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Tolerance to the induction of interferons by endotoxin and virus: role of a humoral factor.
Proc Soc Exp Biol Med. 1965 Aug-Sep;119(4):1227-32. doi: 10.3181/00379727-119-30421.
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Mechanisms of endotoxin tolerance. V. Specificity of the early and late phases of pyrogenic tolerance.内毒素耐受的机制。V. 热原耐受早期和晚期的特异性。
J Immunol. 1969 Dec;103(6):1223-36.
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Endotoxin-induced modification of Plasmodium berghei infection in mice.
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Distribution of endotoxin-51-Cr in normal and endotoxin-resistant dogs.内毒素 - 51铬在正常犬和内毒素抗性犬中的分布
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The stimulation by endotoxin of the nonspecific resistance of mice to bacterial infections.内毒素对小鼠抵抗细菌感染的非特异性抵抗力的刺激作用。
Br J Exp Pathol. 1974 Apr;55(2):194-202.
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