洛哌丁胺（R 18 553），一种新型止泻药。第7部分：临床研究。洛哌丁胺治疗严重慢性腹泻患者的疗效和安全性。 - Suppr

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超能文献

Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 7: Clinical investigation. Efficacy and safety of loperamide in patients with severe chronic diarrhea.

作者信息

Verhaegen H, De Cree J, Schuermans V

出版信息

Arzneimittelforschung. 1974 Oct;24(10):1657-60.

PMID:4611433

Abstract

摘要

相似文献

Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 7: Clinical investigation. Efficacy and safety of loperamide in patients with severe chronic diarrhea.洛哌丁胺（R 18 553），一种新型止泻药。第7部分：临床研究。洛哌丁胺治疗严重慢性腹泻患者的疗效和安全性。

Arzneimittelforschung. 1974 Oct;24(10):1657-60.

Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 8: Clinical investigation. Use of a flexible dosage schedule in a double-blind comparison of loperamide with diphenoxylate in 614 patients suffering from acute diarrhea.洛哌丁胺（R 18 553），一种新型止泻药。第八部分：临床研究。在614例急性腹泻患者中，采用灵活剂量方案对洛哌丁胺与地芬诺酯进行双盲比较。

Arzneimittelforschung. 1974 Oct;24(10):1660-5.

Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 6: Clinical pharmacology. Placebo-controlled comparison of the constipating activity and safety of loperamide, diphenoxylate and codeine in normal volunteers.洛哌丁胺（R 18 553），一种新型止泻药。第6部分：临床药理学。正常志愿者中洛哌丁胺、地芬诺酯和可待因致便秘活性及安全性的安慰剂对照比较。

Arzneimittelforschung. 1974 Oct;24(10):1653-7.

A multicentre double-blind study in acute diarrhoea comparing loperamide (R 18553) with two common antidiarrhoeal agents and a placebo.一项在急性腹泻患者中进行的多中心双盲研究，比较洛哌丁胺（R 18553）与两种常用止泻药及一种安慰剂。

Curr Ther Res Clin Exp. 1975 Mar;17(3):263-70.

A double blind crossover comparison of loperamide with diphenoxylate in the symptomatic treatment of chronic diarrhea.洛哌丁胺与地芬诺酯对症治疗慢性腹泻的双盲交叉比较。

Gastroenterology. 1976 Jun;70(6):1030-4.

Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 5: the pharmacokinetics of loperamide in rats and man.洛哌丁胺（R 18 553），一种新型止泻剂。第5部分：洛哌丁胺在大鼠和人体中的药代动力学。

Arzneimittelforschung. 1974 Oct;24(10):1649-53.

Loperamide: an open multicentre trial and double-blind cross-over comparison with placebo in patients with chronic diarrhoea.洛哌丁胺：一项针对慢性腹泻患者的开放性多中心试验及与安慰剂的双盲交叉对照比较。

Curr Ther Res Clin Exp. 1974 Jan;16(1):32-9.

Loperamide: a new antidiarrheal agent in the treatment of chronic diarrhea.洛哌丁胺：一种治疗慢性腹泻的新型止泻药。

Gastroenterology. 1976 Jun;70(6):1026-9.

Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 1: in vivo oral pharmacology and acute toxicity. Comparison with morphine, codeine, diphenoxylate and difenoxine.洛哌丁胺（R 18 553），一种新型止泻药。第1部分：体内口服药理学及急性毒性。与吗啡、可待因、地芬诺酯和地芬诺辛的比较。

Arzneimittelforschung. 1974 Oct;24(10):1633-6.

Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 4: studies on subacute and chronic toxicity and the effect on reproductive processes in rats, dogs and rabbits.洛哌丁胺（R 18 553），一种新型止泻药。第4部分：大鼠、狗和兔的亚急性和慢性毒性及对生殖过程影响的研究。

Arzneimittelforschung. 1974 Oct;24(10):1645-9.

引用本文的文献

Loperamide, diphenoxylate, and codeine phosphate in chronic diarrhoea.洛哌丁胺、地芬诺酯及磷酸可待因治疗慢性腹泻

Br Med J. 1980 Feb 23;280(6213):524. doi: 10.1136/bmj.280.6213.524.

Loperamide has antisecretory activity in the human jejunum in vivo.洛哌丁胺在人体内空肠具有体内抗分泌活性。

Gut. 1984 Sep;25(9):931-5. doi: 10.1136/gut.25.9.931.

Loperamide: a review of its pharmacological properties and therapeutic efficacy in diarrhoea.洛哌丁胺：其药理学特性及对腹泻治疗效果的综述

Drugs. 1978 Jan;15(1):33-52. doi: 10.2165/00003495-197815010-00003.

Effect of loperamide on fecal output and composition in well-established ileostomy and ileorectal anastomosis.

Am J Dig Dis. 1977 Aug;22(8):669-76. doi: 10.1007/BF01078345.

Double-blind placebo-controlled study of loperamide (Imodium) in chronic diarrhoea caused by ileocolic disease or resection.洛哌丁胺（易蒙停）治疗回结肠疾病或切除术后所致慢性腹泻的双盲安慰剂对照研究

Gut. 1977 Jul;18(7):575-9. doi: 10.1136/gut.18.7.575.

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