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糖化血红蛋白:糖尿病患者对其剂量的需求(作者译)

[HbA1c: need of its dosage in diabetics (author's transl)].

作者信息

Clarke J, Passa P, Canivet J

出版信息

Nouv Presse Med. 1979 Feb 10;8(7):513-7.

PMID:461162
Abstract

HbA1c is the product of a slow, virtually irreversible reaction, occurring continuously throughout the 120 day life-span of the erythrocyte, between HbAo and glucose. It has been shown to represent the time-averaged blood glucose concentration of the preceeding 2 month period, and is independant of day to day fluctuations in the blood glucose concentration. HbA1c therefore acts as a biochemical marker and permits clinicans, by one test, to judge the quality of the diabetic control, in their patients.

摘要

糖化血红蛋白(HbA1c)是血红蛋白A0(HbA0)与葡萄糖之间缓慢且几乎不可逆反应的产物,该反应在红细胞120天的生命周期中持续发生。研究表明,它代表了前两个月期间的平均血糖浓度,且不受血糖浓度每日波动的影响。因此,糖化血红蛋白作为一种生化标志物,使临床医生通过一项检测就能判断患者糖尿病的控制情况。

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