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糖化血红蛋白中的血液浓度。糖尿病控制时间指标(作者译)

[Blood concentration in glycosylated hemoglobin. Index in diabetic control time (author's transl)].

作者信息

Vague P, Vovan L, Vialettes B, Boustieres C, Serin N

出版信息

Nouv Presse Med. 1979 Feb 10;8(7):491-4.

PMID:461160
Abstract

To estimate during which period of time the degree of diabetes control is integrated by the level of glycosylated hemoglobin two approachs were used. Hb-g was assayed by cellulose acetate electrophoresis in insulin-dependent diabetics and compared to the degree of control over a 3 months period. Control was evaluated by the semiquantitative urine test for sugar "Clinitest" three time a day. Hb-g correlated highly with last month glycosuria, but not as well with those of the two preceding months. These later correlation in fact reflected the stability of control over the three months. In 7 incipient insulin dependent diabetics in whom normal glycaemia was achieved abruptly and maintained for more than one month, Hb-g fell to normal within one month and therefore did not reflect the prexisting hyperglycemia. Hb-g integrates precisely the degree of diabetes control, but over a one month period only.

摘要

为了评估糖化血红蛋白水平反映糖尿病控制程度的时间段,采用了两种方法。通过醋酸纤维素电泳对胰岛素依赖型糖尿病患者的糖化血红蛋白(Hb-g)进行检测,并与3个月期间的控制程度进行比较。通过每天三次使用“Clinitest”半定量尿糖试验来评估控制情况。Hb-g与上个月的糖尿高度相关,但与前两个月的糖尿相关性不佳。后一种相关性实际上反映了三个月内控制的稳定性。在7例初发胰岛素依赖型糖尿病患者中,血糖突然恢复正常并维持了一个多月,Hb-g在一个月内降至正常,因此未能反映先前存在的高血糖情况。Hb-g能准确反映糖尿病的控制程度,但仅在一个月的时间段内。

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