Stellpflug H, Kox W, Vietor G, Kubie E
Prakt Anaesth. 1979 Jun;14(3):233-41.
An aerosol of an aqueous solution still changes its size from development up to alveoli; therefore only conclusions can be made about possible sizes of particle spectrum. Volatilisation, condensation, coagulation and sedimentation are the important interfering factors. To characterize an aerosol one should know the aerosolvolume, the quantity of nebulised substance and the relative size distribution. A method for measurement of size distribution -- a radioactive aerosol was deposited in a spiral centrifuge -- is described and the aerosol of two ultrasonic nebulizers were compared. Because of their physical properties aerosols of ultrasonic nebulizers play a main part in prophylaxis and therapy of functional lesion of bronchopulmonary affections.
水溶液气雾剂从产生到肺泡的过程中其大小仍会发生变化；因此，对于颗粒谱的可能大小只能得出结论。挥发、凝结、凝聚和沉降是重要的干扰因素。为了表征气雾剂，应该了解气雾剂的体积、雾化物质的量和相对大小分布。描述了一种测量大小分布的方法——将放射性气雾剂沉积在螺旋离心机中——并比较了两种超声雾化器的气雾剂。由于其物理特性，超声雾化器的气雾剂在支气管肺部疾病功能性病变的预防和治疗中起主要作用。
