Kopp K H, Blanig I, Rabenschlag R, Vogel W
Prax Klin Pneumol. 1979 Apr;33 Suppl 1:493-501.
A statistical analysis of the case material at the Intensive Care Unit, Freiburg, for the years 1975 and 1976 established that 40% and 39% respectively of patients with multiple injuries had also suffered a chest trauma and that the latter was the direct cause of respiratory insufficiency in 61% (1975) and 57% (1976) of patients in need of controlled respiration, i.e. respiratory insufficiency dominated the clinical and pathophysiological picture. The causes were: restricted respiratory movements due to pain, compression of the lungs or pathological changes in the injured lung, and they affected the normal gaseous exchange in a variety of ways. Alveolar hypoventilation with disturbance of ventilation-perfusion, increase in the functional shunt volume, rise in the functional dead space combined with reduced functional residual capacity and compliance result, if left uncorrected, in a drastic increase of resistance on the part of the pulmonary vessels and finally in, often fatal, hyoxaemia and hypercapnia. Regular estimations of the arterial blood gases in air and pure oxygen, of the arterio-alveolar difference in oxygen pressure, shunt volume, dead space and effective compliance of the chest wall and lungs are, therefore, essential. Treatment in an intensive care unit comprises the relief of any acute condition, such as tension pneumothorax, haemothorax, and general measures. Means to relieve pain in patients whose chest injuries are not sufficiently severe to require artificial ventilation are: intercostal blocking, acupuncture or peridural analgesia; efficient breathing exercises are important. The indications for artificial ventilation should be interpreted generously and the decision to perform it should be made at an early stage. The technique is determined by the type of pathological changes in the gaseous exchange and should aim at restoring normal conditions as far as possible.
对弗莱堡重症监护病房1975年和1976年的病例资料进行的统计分析表明,多发伤患者中分别有40%和39%也遭受了胸部创伤,并且在需要控制呼吸的患者中,后者分别是61%(1975年)和57%(1976年)呼吸功能不全的直接原因,即呼吸功能不全主导了临床和病理生理表现。其原因包括:因疼痛导致呼吸运动受限、肺部受压或受伤肺的病理改变,它们以多种方式影响正常的气体交换。肺泡通气不足伴通气/血流比例失调、功能性分流容积增加、功能性死腔增加以及功能残气量和顺应性降低,如果不加以纠正,会导致肺血管阻力急剧增加,最终导致往往致命的低氧血症和高碳酸血症。因此,定期测定空气中和纯氧中的动脉血气、氧分压的动-肺泡差值、分流容积、死腔以及胸壁和肺的有效顺应性至关重要。重症监护病房的治疗包括缓解任何急性病症,如张力性气胸、血胸以及一般措施。对于胸部损伤不太严重无需人工通气的患者,缓解疼痛的方法有:肋间阻滞、针刺或硬膜外镇痛;有效的呼吸锻炼很重要。人工通气的指征应放宽解释,且应尽早做出进行人工通气的决定。人工通气技术取决于气体交换病理改变的类型,应尽可能旨在恢复正常状态。