发展中国家儿童弓形虫感染情况
Acquisition of toxoplasma infection by children in a developing country.
作者信息
Stagno S, Thiermann E
出版信息
Bull World Health Organ. 1973;49(6):627-31.
The prevalence of toxoplasma infection was studied in 850 healthy children (550 newborn infants and 300 children aged 6 months to 14 years) from a population of low socioeconomic status in Santiago, Chile. Antibodies were detected in 49% of the serum samples in children at birth and in 0% at 6 months, 2% at 1 year, 10% at 2 years, 22% at 4 years, and 32% at 6 years of age, and in 48% of the children aged 7-14 years. In order to determine the rate of infection and associated epidemiological factors, 50 seronegative infants aged 6 months were followed up; 11% and 14% of them showed seroconversion after 1 and 2 years, respectively. The results suggest a significant association between infection and the ingestion of raw or undercooked meat. The role of cats and vectors such as flies and cockroaches in the transmission of infection could not be determined owing to the commonness of these two sources in relation to the small number of subjects studied.
对智利圣地亚哥社会经济地位较低人群中的850名健康儿童（550名新生儿和300名6个月至14岁儿童）进行了弓形虫感染率研究。出生时儿童血清样本中49%检测到抗体，6个月时为0%，1岁时为2%，2岁时为10%，4岁时为22%，6岁时为32%，7 - 14岁儿童中48%检测到抗体。为确定感染率及相关流行病学因素，对50名6个月龄血清学阴性婴儿进行随访；分别有11%和14%在1年和2年后出现血清学转换。结果表明感染与食用生肉或未煮熟肉类之间存在显著关联。由于这两种传染源在研究对象中普遍存在且研究对象数量较少，无法确定猫以及苍蝇和蟑螂等病媒在感染传播中的作用。
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