普遍性转导过程中的受体基因重复。
Recipient gene duplication during generalized transduction.
作者信息
Stodolsky M
出版信息
Genetics. 1974 Nov;78(3):809-22. doi: 10.1093/genetics/78.3.809.
An Hfr13 Delta(proA-lac) deletion recipient, -Delta(proA-lac)-F-purE(+)-, has been utilized in a study of the origins of duplications formed during chromosome fragment integration. Among the Pro(-)Lac(+) transductants, some have duplications spanning the F locus. These transductants are, or segregate, strains with F' episomes carrying genes of the duplication. Some of the duplications include purE(+), a gene which is not coinherited with lac(+) during bacteriophage P1-mediated transduction. Thus recipient genes have been duplicated during recombinant formation. Crossing-over models including replication steps provide a basis for explaining the duplication process.
一个Hfr13 Delta(proA-lac)缺失受体菌，即-Delta(proA-lac)-F-purE(+) -，已被用于一项关于染色体片段整合过程中形成重复序列起源的研究。在Pro(-)Lac(+)转导子中，一些转导子具有跨越F位点的重复序列。这些转导子是携带重复序列基因的F'附加体菌株，或者会分离出这样的菌株。一些重复序列包含purE(+)，该基因在噬菌体P1介导的转导过程中不会与lac(+)一起遗传。因此，受体基因在重组形成过程中发生了重复。包括复制步骤的交叉模型为解释重复过程提供了基础。
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