半胱胺、半胱氨酸和二硫代氨基甲酸盐在实验性对乙酰氨基酚中毒中的疗效。 - Suppr

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超能文献

The curative effects of cysteamine, cysteine, and dithiocarb in experimental paracetamol poisoning.

作者信息

Strubelt O, Siegers C P, Schütt A

出版信息

Arch Toxicol. 1974;33(1):55-64. doi: 10.1007/BF00297053.

DOI:10.1007/BF00297053

PMID:4616650

Abstract

摘要

相似文献

The curative effects of cysteamine, cysteine, and dithiocarb in experimental paracetamol poisoning.半胱胺、半胱氨酸和二硫代氨基甲酸盐在实验性对乙酰氨基酚中毒中的疗效。

Arch Toxicol. 1974;33(1):55-64. doi: 10.1007/BF00297053.

Letter: Cysteamine for paracetamol overdosage.信函：半胱胺用于对乙酰氨基酚过量中毒

Lancet. 1974 May 18;1(7864):998.

Cysteamine, methionine, and penicillamine in the treatment of paracetamol poisoning.半胱胺、蛋氨酸及青霉胺用于对乙酰氨基酚中毒的治疗

Lancet. 1976 Jul 17;2(7977):109-13. doi: 10.1016/s0140-6736(76)92842-7.

Proceedings: Controlled trial of cysteamine and dimercaprol in the prevention of liver damage after paracetamol overdose.论文：半胱胺与二巯丙醇预防对乙酰氨基酚过量后肝损伤的对照试验

Gut. 1975 Oct;16(10):839.

Controlled trial of cysteamine and dimercaprol after paracetamol overdose.对乙酰氨基酚过量服用后半胱胺与二巯丙醇的对照试验。

Br Med J. 1977 Nov 26;2(6099):1395. doi: 10.1136/bmj.2.6099.1395.

Letter: B.A.L. in paracetamol poisoning.信件：对乙酰氨基酚中毒时的支气管肺泡灌洗术

Lancet. 1974 Oct 5;2(7884):833-4. doi: 10.1016/s0140-6736(74)91092-7.

Acetaminophen hepatotoxicity.对乙酰氨基酚肝毒性

Gastroenterology. 1980 Feb;78(2):382-92.

[Phalloidin antagonists 4th communication: Thioctic acid, SH-compounds, rifampicin, choleretics, dexamethasone, estradiol, unspecific inhibitors, and ineffective compounds (author's transl)].[鬼笔环肽拮抗剂的第四次通讯：硫辛酸、含巯基化合物、利福平、利胆剂、地塞米松、雌二醇、非特异性抑制剂及无效化合物（作者译）]

Arzneimittelforschung. 1975;25(12):1881-4.

[Paracetamol poisoning--clinical picture and treatment possibilities].

Lakartidningen. 1976 Apr 28;73(18):1723-6, 1728.

Cysteamine, L-methionine and D-penicillamine in paracetamol poisoning.半胱胺、L-甲硫氨酸和青霉胺用于对乙酰氨基酚中毒治疗

J Int Med Res. 1976;4(4 Suppl):112-7. doi: 10.1177/14732300760040S420.

引用本文的文献

-Cystamine: A Deuterated Cystamine Derivative with Improved Anti-Inflammatory and Anti-Fibrotic Activities in a Murine Model of Fibrosing Steatohepatitis.-半胱胺：一种氘代半胱胺衍生物，在纤维化性脂肪性肝炎小鼠模型中具有增强的抗炎和抗纤维化活性。

ACS Pharmacol Transl Sci. 2025 Feb 24;8(3):885-898. doi: 10.1021/acsptsci.4c00738. eCollection 2025 Mar 14.

Cysteamine, an Endogenous Aminothiol, and Cystamine, the Disulfide Product of Oxidation, Increase Pseudomonas aeruginosa Sensitivity to Reactive Oxygen and Nitrogen Species and Potentiate Therapeutic Antibiotics against Bacterial Infection.半胱胺，一种内源性的含硫氨基酸，和胱胺，氧化的二硫产物，增加铜绿假单胞菌对活性氧和氮物种的敏感性，并增强治疗细菌感染的抗生素的疗效。

Infect Immun. 2018 May 22;86(6). doi: 10.1128/IAI.00947-17. Print 2018 Jun.

Mass spectrometric analysis of L-cysteine metabolism: physiological role and fate of L-cysteine in the enteric protozoan parasite Entamoeba histolytica.L-半胱氨酸代谢的质谱分析：肠道原生动物寄生虫溶组织内阿米巴中L-半胱氨酸的生理作用和去向

mBio. 2014 Nov 4;5(6):e01995. doi: 10.1128/mBio.01995-14.

Effect of thiola on acetaminophen induced hepatic necrosis in mice.

Bull Environ Contam Toxicol. 1993 Dec;51(6):808-13. doi: 10.1007/BF00198274.

Paracetamol.对乙酰氨基酚

Postgrad Med J. 1980 Jul;56(657):459-73. doi: 10.1136/pgmj.56.657.459.

Paracetamol overdosage. Pharmacological considerations and clinical management.对乙酰氨基酚过量。药理学考量与临床处理

Drugs. 1983 Mar;25(3):290-314. doi: 10.2165/00003495-198325030-00002.

Effect of diethyldithiocarbamate on the metabolic elimination of hexobarbital, phenazone, tolbutamide and four halogenated hydrocarbons.二乙二硫代氨基甲酸盐对己巴比妥、非那宗、甲苯磺丁脲及四种卤代烃代谢消除的影响。

Eur J Drug Metab Pharmacokinet. 1981;6(2):141-8. doi: 10.1007/BF03189481.

Inhibition of the hepatotoxicity of paracetamol and its irreversible binding to rat liver microsomal protein.对乙酰氨基酚肝毒性的抑制作用及其与大鼠肝脏微粒体蛋白的不可逆结合。

Arch Toxicol. 1980 May;45(1):61-5. doi: 10.1007/BF00303296.

Selective inhibition of acetaminophen oxidation and toxicity by cimetidine and other histamine H2-receptor antagonists in vivo and in vitro in the rat and in man.西咪替丁及其他组胺H2受体拮抗剂在大鼠和人体体内及体外对乙酰氨基酚氧化和毒性的选择性抑制作用。

J Clin Invest. 1984 Feb;73(2):383-91. doi: 10.1172/JCI111223.

Non-narcotic analgesics. Problems of overdosage.非麻醉性镇痛药。过量用药问题。

Drugs. 1986;32 Suppl 4:177-205. doi: 10.2165/00003495-198600324-00013.

本文引用的文献

A simplified method of evaluating dose-effect experiments.一种评估剂量效应实验的简化方法。

J Pharmacol Exp Ther. 1949 Jun;96(2):99-113.

[THE LIVER PROTECTIVE EFFECT OF CYSTEINE, HOMOCYSTEINE THIOLACTONE AND N-ACETYLHOMOCYSTEINE THIOLACTONE IN EXPERIMENTAL LIVER DAMAGE].

Arzneimittelforschung. 1963 Oct;13:867-71.

[Relation between liver protection and sugar metabolism].

Arzneimittelforschung. 1958 Feb;8(2):72-6.

[Significance of sulfhydryl, amino and carboxyl groups in nectrotropic liver protective action of short-chain hydrocarbons].

Arzneimittelforschung. 1957 Oct;7(10):601-6.

[Cysteine, homocysteine, cystathionine & cysteinamine as necrotropic liver protective substances, combined with glucose & fructose].[半胱氨酸、同型半胱氨酸、胱硫醚及半胱胺作为促坏死性肝脏保护物质，与葡萄糖和果糖联合使用]

Medizinische. 1957 Apr 27(17):618-23.

The relationship between chemical structure and protective effect of dithiocarbamate derivatives against experimental hepatic injury induced by carbon tetrachloride administration in rats.

Biochem Pharmacol. 1966 Jun;15(6):756-8. doi: 10.1016/0006-2952(66)90013-x.

Acute liver necrosis following overdose of paracetamol.对乙酰氨基酚过量导致的急性肝坏死。

Br Med J. 1966 Aug 27;2(5512):497-9. doi: 10.1136/bmj.2.5512.497.

The metabolism of acetophenetidine. Isolation and characterization of S-(1-acetamido-4-hydroxyphenyl)-cysteine, a metabolite of acetophenetidine.非那西丁的代谢。S-(1-乙酰氨基-4-羟基苯基)-半胱氨酸的分离与鉴定，非那西丁的一种代谢产物。

Biochem J. 1964 Sep;92(3):639-43. doi: 10.1042/bj0920639.

Acute paracetamol poisoning.对乙酰氨基酚急性中毒

Br Med J. 1970 Sep 5;3(5722):557-8. doi: 10.1136/bmj.3.5722.557.

Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione.对乙酰氨基酚诱导的肝坏死。IV. 谷胱甘肽的保护作用。

J Pharmacol Exp Ther. 1973 Oct;187(1):211-7.

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