Reed W B, Boder E, Gardner M
Birth Defects Orig Artic Ser. 1974;10(4):265-84.
There are a great number of genetic and congenital disorders with skin manifestations ("genodermatoses") with tumor formation. Some of these tumors are benign (hamartomas, in part) and others are malignant. There is a large group of heredodegenerative disorders with such complications as lymphosarcoma and leukemia. There are congenital tumors with malignancy developing. Lastly, there are the chromosomal abnormalities with skin manifestations and tumors, usually malignant. This will be an ever increasing field and the use of fibroblast and virus cultures will become more important in ascertaining the cause of malignancy.
有大量具有皮肤表现（“遗传性皮肤病”）并伴有肿瘤形成的遗传和先天性疾病。其中一些肿瘤是良性的（部分为错构瘤），另一些则是恶性的。有一大类遗传性退行性疾病会并发淋巴肉瘤和白血病等。存在先天性肿瘤并发展为恶性肿瘤的情况。最后，还有伴有皮肤表现和肿瘤（通常为恶性）的染色体异常。这将是一个不断发展的领域，在确定恶性肿瘤病因方面，成纤维细胞和病毒培养的应用将变得更加重要。
