Barnard C N, Barnard M S
Isr J Med Sci. 1975 Feb-Mar;11(2-3):116-21.
The success of total repair of tetralogy of Fallot depends on a clear understanding of the morbid anatomy and deranged hemodynamics of this anomaly, which consists essentially of two abnormalities, namely, a large unrestrictive ventricular septal defect and a severe obstruction to the outflow of the right ventricle. The ventricular septal defect acts as a safety valve and, therefore, cannot be closed unless the obstruction to the outflow of the right ventricle is adequately relieved. In severe cases, this often necessitates reconstruction of the outflow. With an adequate bypass technique and a clear understanding of the principles described in this article, complete correction of tetralogy of Fallot can be accomplished with a low mortality. In a series of 100 consecutive patients presented, the mortality was only 3%.
法洛四联症全修复术的成功取决于对该畸形的病理解剖和紊乱血流动力学的清晰认识,该畸形主要由两个异常组成,即一个大的非限制性室间隔缺损和右心室流出道严重梗阻。室间隔缺损起到安全阀的作用,因此,除非右心室流出道梗阻得到充分缓解,否则不能关闭。在严重病例中,这通常需要重建流出道。有了适当的体外循环技术和对本文所述原则的清晰理解,法洛四联症的完全矫正可以在低死亡率的情况下完成。在连续呈现的100例患者系列中,死亡率仅为3%。