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1
TEMPERATURE-SENSITIVE MUTANTS OF BACTERIOPHAGE T4D: THEIR ISOLATION AND GENETIC CHARACTERIZATION.噬菌体T4D的温度敏感突变体：其分离与遗传特性
Genetics. 1964 Apr;49(4):649-62. doi: 10.1093/genetics/49.4.649.
2
ABSENCE OF RIBOSOMAL RNA SYNTHESIS IN THE ANUCLEOLATE MUTANT OF XENOPUS LAEVIS.非洲爪蟾无核仁突变体中核糖体RNA合成的缺失
Proc Natl Acad Sci U S A. 1964 Jan;51(1):139-46. doi: 10.1073/pnas.51.1.139.
3
Temperature-sensitive mutations in Drosophila melanogaster. II. Frequency among second chromosome recessive lethals induced by ethyl methanesulfonate.黑腹果蝇中的温度敏感突变。II. 甲磺酸乙酯诱导的第二染色体隐性致死突变中的频率。
Can J Genet Cytol. 1968 Jun;10(2):412-20. doi: 10.1139/g68-055.
4
Temperature-sensitive mutations in Drosophila melanogaster.黑腹果蝇中的温度敏感突变
Science. 1970 Nov 13;170(3959):695-706. doi: 10.1126/science.170.3959.695.
5
Temperature-sensitive mutations in Drosophila melanogaster. 3. Dominant lethals and semilethals on chromosome 2.黑腹果蝇中的温度敏感突变。3. 染色体2上的显性致死和半致死突变
Proc Natl Acad Sci U S A. 1969 Feb;62(2):369-76. doi: 10.1073/pnas.62.2.369.
6
Temperature-sensitive mutations in Drosophila melanogaster,I. Relative frequencies among gamma-ray and chemically induced sex-linked recessive lethals and semilethals.黑腹果蝇中的温度敏感突变，I. γ射线和化学诱导的性连锁隐性致死突变和半致死突变的相对频率。
Proc Natl Acad Sci U S A. 1967 Apr;57(4):907-12. doi: 10.1073/pnas.57.4.907.
7
Structure and function of E. coli ribosomes. 8. Cold-sensitive mutants defective in ribosome assembly.大肠杆菌核糖体的结构与功能。8. 核糖体组装缺陷的冷敏感突变体。
Proc Natl Acad Sci U S A. 1969 Jun;63(2):384-91. doi: 10.1073/pnas.63.2.384.

黑腹果蝇中的温度敏感突变。IX. 常染色体上的显性冷敏感致死基因。

Temperature-sensitive mutations in Drosophila melanogaster. IX. Dominant cold-sensitive lethals on the autosomes.

作者信息

Rosenbluth R, Ezell D, Suzuki D T

出版信息

Genetics. 1972 Jan;70(1):75-86. doi: 10.1093/genetics/70.1.75.

DOI:10.1093/genetics/70.1.75
PMID:4622446
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1212724/
Abstract

Ethyl methanesulfonate-treated autosomes were screened for the presence of dominant cold-sensitive (DCS) lethal mutations in Drosophila melanogaster. None was found among 6,552 treated and 168 untreated third chromosomes. Twenty-three DCS-L chromosomes which caused death at 17 degrees C but survived at 22 degrees C and 29 degrees C were recovered from 5,046 mutagenized chromosome 2's.-The DCS-L mutations all mapped around dp and appeared to be functionally allelic. Lethality of heterozygotes for most of the DCS-L's occurred over a prolonged interval from the embryonic through the larval instars. Prolonged incubation at 17 degrees C did not demonstrate any maternal effect on zygotic survival.

摘要

对经甲磺酸乙酯处理的常染色体进行筛选，以检测黑腹果蝇中显性冷敏感（DCS）致死突变的存在。在6552条经处理的和168条未经处理的第三染色体中均未发现此类突变。从5046条经诱变的第二染色体中获得了23条DCS-L染色体，这些染色体在17℃时致死，但在22℃和29℃时存活。-DCS-L突变均定位在dp附近，且似乎在功能上是等位基因。大多数DCS-L杂合子的致死性发生在从胚胎期到幼虫龄期的较长时间段内。在17℃下长时间孵育未显示对合子存活有任何母体效应。