慢性肾衰竭非透析患者和透析患者的全身钾含量。
Total body potassium in non-dialysed and dialysed patients with chronic renal failure.
作者信息
Boddy K, King P C, Lindsay R M, Briggs J D, Winchester J F, Kennedy A C
出版信息
Br Med J. 1972 Mar 25;1(5803):771-5. doi: 10.1136/bmj.1.5803.771.
Total body potassium was studied in 33 patients with chronic renal failure, 18 of whom had been receiving regular dialysis therapy for 1 to 48 months. In nondialysed patients body potassium was not significantly different from normal in the group as a whole, but was significantly greater than normal in three patients, and significantly less than normal in two patients. In 14 of the dialysed patients, both as individuals and as a group, body potassium was not significantly different from normal but in the remaining four it was less than normal.Potassium transfer during dialysis was studied in two patients. Uptake by these two patients of (43)K added to the dialysate (1 mEq K/litre) was measured by whole-body monitoring. Transfer of administered (43)K from the patients to the dialysate was measured by whole-body monitoring and by radioactive and chemical assay of the dialysate. A negative balance due to twice-weekly dialysis of 178 and 244 mEq K/week was found, which with weekly faecal and urine losses of 20-30 mEq K approximately equals the dietary intake of 210-315 mEq K.
对33例慢性肾衰竭患者的全身钾含量进行了研究，其中18例接受常规透析治疗1至48个月。在未透析的患者中，总体而言身体钾含量与正常水平无显著差异，但有3例患者的身体钾含量显著高于正常水平，2例患者的身体钾含量显著低于正常水平。在14例已透析的患者中，无论是个体还是作为一个群体，身体钾含量与正常水平无显著差异，但其余4例患者的身体钾含量低于正常水平。对2例患者透析期间的钾转移情况进行了研究。通过全身监测测量这2例患者对添加到透析液（1 mEq钾/升）中的（43）钾的摄取量。通过全身监测以及对透析液进行放射性和化学分析来测量给予患者的（43）钾向透析液中的转移情况。发现每周进行两次透析导致的钾负平衡分别为178和244 mEq钾/周，加上每周粪便和尿液中损失的20 - 30 mEq钾，大致相当于饮食摄入量210 - 315 mEq钾。
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