[Formation of 7-dehydrocholesterol ketoderivative - cholesta-4,7-dien-3-one in stomach and intestinal rat tissues].

Incorporation of [2-14C] sodium acetate into 7-dehydrocholesterol ketoderivative, cholesta-4,7-dien-3-on, was studied in the tissues of the rat stomach secretory and esophageal parts and in the mucous and serous membranes of the small intestine. Cholesta-4,7-dien-3-on is shown to form not from [14C]cholesterol but from [14C] dehydrocholesterol. Incorporation of the label into the compound under study is established to be maximum 6h after isotope administration. The formation of cholesta-4,7-dien-3-on is the most active in the mucous membrane of small intestine and secretory part of the stomach. An assumption is advanced on the relation between the oxidative transformation of 7-dehydrocholesterol and secretion of hydrochloric acid by the animal mucous tissue.