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某些物理和化学因素影响下麻疹疫苗的稳定性

Stability of antimeasles vaccine under the influence of some physical and chemical factors.

作者信息

Sorodoc Y, Cernescu C, Aderca I

出版信息

Virologie. 1979 Apr-Jun;30(2):135-8.

PMID:462792
Abstract

A study on the stability of lyophilized and rehydrated measles vaccines under the influence of temperature and light was undertaken. After rehydration there was a considerable decrease in the potency of the vaccine, even when stored at +4 degrees C-- +8 DEGREES C and in the dark. Out of the several drugs tested, the commercially available drug AS was found to have a stabilizing effect on measles vaccine infectivity.

摘要

开展了一项关于冻干和复水后麻疹疫苗在温度和光照影响下稳定性的研究。复水后,即使疫苗储存在4摄氏度至8摄氏度且处于黑暗环境中,其效力也会大幅下降。在测试的几种药物中,发现市售药物AS对麻疹疫苗的感染力具有稳定作用。

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