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血友病患者中同种免疫和对冷沉淀过敏反应的发生率。

Incidence of allo-immunization and allergic reactions to cryoprecipitate in haemophilia.

作者信息

McVerry B A, Machin S J

出版信息

Vox Sang. 1979;36(2):77-80. doi: 10.1111/j.1423-0410.1979.tb04402.x.

DOI:10.1111/j.1423-0410.1979.tb04402.x
PMID:462899
Abstract

38 haemophiliacs who had received frequent cryoprecipitate infusions, were investigated for the presence of antibodies directed against red cell, HLA, Gm, Inv and platelet-specific antigens. 15 had detectable antibodies against one or more antigen systems. 11 experienced allergic reactions following infusions of cryoprecipitate. There was no correlation between allergic reactions and the presence of detectable antibodies.

摘要

对38名频繁接受冷沉淀输注的血友病患者进行了调查,以检测其针对红细胞、人类白细胞抗原(HLA)、Gm、Inv和血小板特异性抗原的抗体。15名患者检测到针对一种或多种抗原系统的抗体。11名患者在输注冷沉淀后出现过敏反应。过敏反应与可检测到的抗体之间没有相关性。

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