Katz J, Marcus R G
Br Med J. 1972 Sep 16;3(5828):667-9. doi: 10.1136/bmj.3.5828.667.
In 9 (24%) out of 38 African women who had suffered a ruptured tubal pregnancy significant numbers of fetal erythrocytes (5 or more per 150,000 maternal cells) were found in the maternal circulation. This is a higher incidence than occurs after abortion and indicates that rupture of a tubal pregnancy is a potential source of Rh isoimmunization. The finding of fetal cells in the peritoneal cavity suggests that this is the main source of the fetal blood found in the maternal circulation. At operation on Rh-negative patients with ruptured tubal pregnancies, therefore, complete removal of the peritoneal blood should be attempted and the blood recovered should never be transfused into the patient, who should always receive prophylactic Rh immunoglobulin.
在38例曾患输卵管妊娠破裂的非洲女性中，有9例（24%）在母体循环中发现了大量胎儿红细胞（每150,000个母体细胞中有5个或更多）。这一发生率高于流产后出现的情况，表明输卵管妊娠破裂是Rh血型同种免疫的一个潜在来源。在腹腔中发现胎儿细胞表明，这是母体循环中发现的胎儿血液的主要来源。因此，对于输卵管妊娠破裂的Rh阴性患者进行手术时，应尝试彻底清除腹腔内的血液，回收的血液绝不应输给患者，患者应始终接受预防性Rh免疫球蛋白治疗。
