甲型流感神经氨酸酶致敏红细胞抗体检测
Influenza A neuraminidase antibody assay with sensitized erythrocytes.
作者信息
Holston J L, Dowdle W R
出版信息
Appl Microbiol. 1973 Jan;25(1):97-102. doi: 10.1128/am.25.1.97-102.1973.
Abstract
Erythrocytes sensitized with purified neuraminidase (Hong Kong) antigens were used for assay of influenza A neuraminidase antibodies. The neuraminidase indirect hemagglutination test was equal to the neuraminidase hemagglutination-inhibition (enhancement) test and appeared to be better than the neuraminidase inhibition test for detection of fourfold or greater antibody rises in paired sera from influenza patients or vaccinees. It was better than both tests for detection of neuraminidase antibody. The neuraminidase indirect hemagglutination test is simple to perform and has the advantage of direct antigen-antibody assay.
摘要
用纯化的神经氨酸酶（香港株）抗原致敏的红细胞用于甲型流感神经氨酸酶抗体的检测。神经氨酸酶间接血凝试验与神经氨酸酶血凝抑制（增强）试验相当，并且在检测流感患者或疫苗接种者配对血清中四倍或更高倍数的抗体升高方面似乎优于神经氨酸酶抑制试验。在检测神经氨酸酶抗体方面，它比这两种试验都要好。神经氨酸酶间接血凝试验操作简单，具有直接抗原抗体检测的优点。
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