Shannon M P, Kaufman T C, Shen M W, Judd B H
Genetics. 1972 Dec;72(4):615-38. doi: 10.1093/genetics/72.4.615.
Aspects of the developmental genetics of lethal and semi-lethal mutants representing 13 complementation groups (cistrons) in the 3A-3C region of the X chromosome of Drosophila melanogaster are given. Each of these cistrons is associated with a particular chromomere in the salivary gland chromosome. Mutants within each cistron have similar lethality patterns and morphological attributes, and the characteristics of a given cistron are distinct with respect to other cistrons. These results provide additional evidence that only one function is associated with each chromomere.-The results of the lethality pattern analysis are also compared with previous studies of lethal mutants of Drosophila.
本文给出了黑腹果蝇X染色体3A-3C区域中代表13个互补群(顺反子)的致死和半致死突变体的发育遗传学方面的内容。这些顺反子中的每一个都与唾液腺染色体中的一个特定染色粒相关联。每个顺反子内的突变体具有相似的致死模式和形态学特征,并且给定顺反子的特征相对于其他顺反子是不同的。这些结果提供了额外的证据,即每个染色粒仅与一种功能相关联。-致死模式分析的结果也与果蝇致死突变体的先前研究进行了比较。