乳胶凝集试验在脑膜炎球菌性脑膜炎诊断中的应用
Latex agglutination in the diagnosis of meningococcal meningitis.
作者信息
Severin W P
出版信息
J Clin Pathol. 1972 Dec;25(12):1079-82. doi: 10.1136/jcp.25.12.1079.
Abstract
Group-specific polysaccharides of Neisseria meningitidis groups A and C have been demonstrated by means of a rapid, sensitive slide agglutination test with latex particles coated with antibodies. In this manner, the diagnosis can be made from the cerebrospinal fluid of patients with meningococcal meningitis caused by serogroups A or C even when the culture is negative. The method appears to be more sensitive than countercurrent immunoelectrophoresis and less elaborate.
摘要
通过用包被抗体的乳胶颗粒进行快速、灵敏的玻片凝集试验，已证实了A群和C群脑膜炎奈瑟菌的群特异性多糖。用这种方法，即使培养结果为阴性，也能从A群或C群血清型引起的脑膜炎球菌性脑膜炎患者的脑脊液中做出诊断。该方法似乎比对流免疫电泳更灵敏，且操作更简便。
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