环氧化物水解酶的诱导、激活与抑制：环氧化物水解酶抑制剂对氯苯诱导的肝毒性的异常预防作用 - Suppr

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Induction, activation and inhibition of epoxide hydrase: an anomalous prevention of chlorobenzene-induced hepatotoxicity by an inhibitor of epoxide hydrase.

作者信息

Oesch F, Jerina D M, Daly J W, Rice J M

出版信息

Chem Biol Interact. 1973 Mar;6(3):189-202. doi: 10.1016/0009-2797(73)90071-9.

DOI:10.1016/0009-2797(73)90071-9

PMID:4632460

Abstract

摘要

相似文献

Induction, activation and inhibition of epoxide hydrase: an anomalous prevention of chlorobenzene-induced hepatotoxicity by an inhibitor of epoxide hydrase.

Chem Biol Interact. 1973 Mar;6(3):189-202. doi: 10.1016/0009-2797(73)90071-9.

Epoxide hydrase in human liver biopsy specimens: assay and properties.

Biochem Pharmacol. 1974 Apr 15;23(8):1307-17. doi: 10.1016/0006-2952(74)90333-5.

A radiometric assay for hepatic epoxide hydrase activity with [7-3H] styrene oxide.

Biochim Biophys Acta. 1971 Mar 10;227(3):685-91. doi: 10.1016/0005-2744(71)90017-9.

Hepatic and extrahepatic metabolism of 14C-styrene oxide.

Environ Health Perspect. 1976 Oct;17:135-44. doi: 10.1289/ehp.7617135.

Characterization of rat lung epoxide (styrene oxide) hydrase with a modified radioactive assay of improved sensitivity.

Cancer Res. 1977 Apr;37(4):1075-82.

Hepatic epoxide hydrase in neonatal and partially hepatectomized rats.

Cancer Res. 1974 Oct;34(10):2810-3.

Solubilization, purification, and properties of a hepatic epoxide hydrase.

Biochim Biophys Acta. 1971 Mar 10;227(3):692-7. doi: 10.1016/0005-2744(71)90018-0.

Presence and induction of epoxide hydrase in cultured human leukocytes.

Biochem Biophys Res Commun. 1973 Jun 8;52(3):712-6. doi: 10.1016/0006-291x(73)90995-9.

Genetic expression of the induction of epoxide hydrase and aryl hydrocarbon hydroxylase activities in the mouse by phenobarbital or 3-methylcholanthrene.

Mol Pharmacol. 1973 Sep;9(5):629-6.

Hydration of arene and alkene oxides by epoxide hydrase in human liver microsomes.

Clin Pharmacol Ther. 1977 Feb;21(2):158-65. doi: 10.1002/cpt1977212158.

引用本文的文献

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mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence.

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The Multifaceted Role of Epoxide Hydrolases in Human Health and Disease.

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The 2014 Bernard B. Brodie award lecture-epoxide hydrolases: drug metabolism to therapeutics for chronic pain.

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Immuno-electron-microscopic studies on the subcellular distribution of rat liver epoxide hydrolase and the effect of phenobarbitone and 2-acetamidofluorene treatment.

Biochem J. 1982 Mar 15;202(3):677-86. doi: 10.1042/bj2020677.

Comparative biology of test species.

Environ Health Perspect. 1988 Apr;77:55-62. doi: 10.1289/ehp.887755.

In vitro covalent binding of the pyrethroids cismethrin, cypermethrin and deltamethrin to rat liver homogenate and microsomes.

Arch Toxicol. 1989;63(3):214-20. doi: 10.1007/BF00316371.

General aspects on biotransformation and elimination of organic compounds in connection with occupational exposure.

Int Arch Occup Environ Health. 1975 Aug 14;35(2):89-115. doi: 10.1007/BF01848257.

Inducible monooxygenase activities and 3-methyl-cholanthrene-initiated tumorigenesis in mouse recombinant inbred sublines.

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Induction, activation and inhibition of epoxide hydrase: an anomalous prevention of chlorobenzene-induced hepatotoxicity by an inhibitor of epoxide hydrase.

作者信息

Oesch F, Jerina D M, Daly J W, Rice J M

出版信息

Chem Biol Interact. 1973 Mar;6(3):189-202. doi: 10.1016/0009-2797(73)90071-9.

DOI:10.1016/0009-2797(73)90071-9

PMID:4632460

Abstract

摘要

相似文献

Induction, activation and inhibition of epoxide hydrase: an anomalous prevention of chlorobenzene-induced hepatotoxicity by an inhibitor of epoxide hydrase.

Chem Biol Interact. 1973 Mar;6(3):189-202. doi: 10.1016/0009-2797(73)90071-9.

Epoxide hydrase in human liver biopsy specimens: assay and properties.

Biochem Pharmacol. 1974 Apr 15;23(8):1307-17. doi: 10.1016/0006-2952(74)90333-5.

A radiometric assay for hepatic epoxide hydrase activity with [7-3H] styrene oxide.

Biochim Biophys Acta. 1971 Mar 10;227(3):685-91. doi: 10.1016/0005-2744(71)90017-9.

Hepatic and extrahepatic metabolism of 14C-styrene oxide.

Environ Health Perspect. 1976 Oct;17:135-44. doi: 10.1289/ehp.7617135.

Characterization of rat lung epoxide (styrene oxide) hydrase with a modified radioactive assay of improved sensitivity.

Cancer Res. 1977 Apr;37(4):1075-82.

Hepatic epoxide hydrase in neonatal and partially hepatectomized rats.

Cancer Res. 1974 Oct;34(10):2810-3.

Solubilization, purification, and properties of a hepatic epoxide hydrase.

Biochim Biophys Acta. 1971 Mar 10;227(3):692-7. doi: 10.1016/0005-2744(71)90018-0.

Presence and induction of epoxide hydrase in cultured human leukocytes.

Biochem Biophys Res Commun. 1973 Jun 8;52(3):712-6. doi: 10.1016/0006-291x(73)90995-9.

Genetic expression of the induction of epoxide hydrase and aryl hydrocarbon hydroxylase activities in the mouse by phenobarbital or 3-methylcholanthrene.

Mol Pharmacol. 1973 Sep;9(5):629-6.

Hydration of arene and alkene oxides by epoxide hydrase in human liver microsomes.

Clin Pharmacol Ther. 1977 Feb;21(2):158-65. doi: 10.1002/cpt1977212158.

引用本文的文献

The prognostic significance of epoxide hydrolases in colorectal cancer.

Biochem Biophys Rep. 2025 Jan 1;41:101912. doi: 10.1016/j.bbrep.2024.101912. eCollection 2025 Mar.

Folic Acid-Modified miR-491-5p-Loaded ZIF-8 Nanoparticles Inhibit Castration-Resistant Prostate Cancer by Regulating the Expression of EPHX1.

Front Bioeng Biotechnol. 2021 Nov 22;9:706536. doi: 10.3389/fbioe.2021.706536. eCollection 2021.

mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence.

Elife. 2021 Aug 3;10:e68445. doi: 10.7554/eLife.68445.

The Multifaceted Role of Epoxide Hydrolases in Human Health and Disease.

Int J Mol Sci. 2020 Dec 22;22(1):13. doi: 10.3390/ijms22010013.

The 2014 Bernard B. Brodie award lecture-epoxide hydrolases: drug metabolism to therapeutics for chronic pain.

Drug Metab Dispos. 2015 May;43(5):788-802. doi: 10.1124/dmd.115.063339. Epub 2015 Mar 11.

Immuno-electron-microscopic studies on the subcellular distribution of rat liver epoxide hydrolase and the effect of phenobarbitone and 2-acetamidofluorene treatment.

Biochem J. 1982 Mar 15;202(3):677-86. doi: 10.1042/bj2020677.

Comparative biology of test species.

Environ Health Perspect. 1988 Apr;77:55-62. doi: 10.1289/ehp.887755.

In vitro covalent binding of the pyrethroids cismethrin, cypermethrin and deltamethrin to rat liver homogenate and microsomes.

Arch Toxicol. 1989;63(3):214-20. doi: 10.1007/BF00316371.

General aspects on biotransformation and elimination of organic compounds in connection with occupational exposure.

Int Arch Occup Environ Health. 1975 Aug 14;35(2):89-115. doi: 10.1007/BF01848257.

Inducible monooxygenase activities and 3-methyl-cholanthrene-initiated tumorigenesis in mouse recombinant inbred sublines.

Genetics. 1976 Jul;83(3 PT.2):537-50.