Howard C J, Gourlay R N, Brownlie J
J Hyg (Lond). 1973 Mar;71(1):163-70. doi: 10.1017/s0022172400046337.
The virulence of T-mycoplasmas for cattle was tested by examining their ability to produce mastitis in cows. It was found that both virulent and avirulent strains of T-mycoplasmas can be isolated from cattle. All of four strains from pneumonic calf lungs and a strain from a case of bovine kerato-conjunctivitis caused mastitis but only two of four strains isolated from the urogenital tract of cows were virulent. None of the human, simian or canine T-mycoplasmas examined were able to cause mastitis in cattle. However, a bovine strain was found to be capable of causing mastitis in goats. Virulent and avirulent strains from the same and different species contain common antigens detected by the metabolic inhibition test. Pathogenicity could not be shown to be characteristic of any particular serotype. The possibility is raised of some species barrier being responsible for the inability of non-bovine strains to infect cattle.
通过检测T支原体在奶牛中引发乳腺炎的能力,对其对牛的毒力进行了测试。结果发现,从牛身上既能分离出有毒力的T支原体菌株,也能分离出无毒力的菌株。来自肺炎小牛肺部的所有四株菌株以及来自一例牛角膜结膜炎病例的一株菌株都引发了乳腺炎,但从奶牛生殖道分离出的四株菌株中只有两株有毒力。所检测的人、猴或犬的T支原体均不能在牛身上引发乳腺炎。然而,发现一株牛源菌株能够在山羊身上引发乳腺炎。来自相同和不同物种的有毒力和无毒力菌株含有通过代谢抑制试验检测到的共同抗原。致病性并未表现为任何特定血清型的特征。由此提出一种可能性,即某些物种屏障导致非牛源菌株无法感染牛。