Wildenthal K, Leshin S J, Atkins J M, Skelton C L
Lancet. 1975 Jan 4;1(7897):12-4. doi: 10.1016/s0140-6736(75)92374-0.
Induction of the diving reflex, by immersion of the face in cold water (2 degrees C) while the breath was held, converted paroxysmal atrial tachycardia to sinus rhythm within 15-35 seconds in seven patients (aged 22-66). Four had histories of heart attacks that had previously required vasopressor therapy, and two had been digitalised; three had no history of prior paroxysmal atrial tachycardia or heart-disease. The reported procedure, which is convenient, non-invasive, and can be self administered by the patient after brief instruction, may offer a useful adjunct to carotid-sinus massage and intravenous infusion of vasopressors for the treatment of paroxysmal atrial tachycardia.
在屏气时将面部浸入冷水（2摄氏度）诱导潜水反射，7例患者（年龄22 - 66岁）在15 - 35秒内将阵发性房性心动过速转为窦性心律。其中4例有心脏病发作史，之前需要血管加压药治疗，2例已接受洋地黄化治疗；3例无前发性阵发性房性心动过速或心脏病史。所报道的方法简便、无创，患者经简短指导后可自行操作，对于阵发性房性心动过速的治疗，可能是颈动脉窦按摩和静脉注射血管加压药的有益辅助方法。
