果蝇的缺口基因座是串联重复序列吗？选定突变的遗传图谱与互补模式的相关性。
Is the notch locus of Drosophila melanogaster a tandem repeat? Correlation of the genetic map and complementation pattern of selected mutations.
作者信息
Foster G G
出版信息
Genetics. 1973 Mar;73(3):435-8. doi: 10.1093/genetics/73.3.435.
Abstract
Correlation of the complementation relationships between the Notch locus alleles fa(g), fa(no), Ax(59d) and nd, with their genetic map order, suggests a tandem repetition within the locus of functionally related sites. This observation is discussed in relation to two hypotheses: (1) that the Notch locus contains a tandem repeat of genetic material; and (2) that the tertiary structure of the Notch locus product has a spiral configuration.
摘要
Notch基因座等位基因fa(g)、fa(no)、Ax(59d)和nd之间的互补关系与其遗传图谱顺序的相关性表明，该基因座内存在功能相关位点的串联重复。结合以下两个假说来讨论这一观察结果：（1）Notch基因座包含遗传物质的串联重复；（2）Notch基因座产物的三级结构具有螺旋构型。
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引用本文的文献
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Allelic negative complementation at the Abruptex locus of Drosophila melanogaster.黑腹果蝇无交叉脉翅位点的等位基因负互补。
Genetics. 1975 Sep;81(1):121-33. doi: 10.1093/genetics/81.1.121.
本文引用的文献
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A PRELIMINARY INVESTIGATION OF PSEUDOALLELISM AT THE NOTCH LOCUS OF Drosophila Melanogaster.黑腹果蝇Notch基因座拟等位现象的初步研究
Proc Natl Acad Sci U S A. 1958 Mar;44(3):254-8. doi: 10.1073/pnas.44.3.254.
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Pseudoallelism at the notch locus in drosophila.果蝇缺刻基因座的拟等位现象。
Genetics. 1962 Jun;47(6):743-59. doi: 10.1093/genetics/47.6.743.
3
Temperature-sensitive mutations in Drosophila melanogaster. IV. A mutation affecting eye facet arrangement in a polarized manner.黑腹果蝇中的温度敏感突变。IV. 一个以极化方式影响眼小面排列的突变。
Proc Natl Acad Sci U S A. 1970 Oct;67(2):738-45. doi: 10.1073/pnas.67.2.738.
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