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Structure-activity correlations between hydroxamic acids and their inhibitory powers on urease activity. I. A quantitative approach to the effect of hydrophobic character of acyl residue.

作者信息

Kumaki K, Tomioka S, Kobashi K, Hase J

出版信息

Chem Pharm Bull (Tokyo). 1972 Aug;20(8):1599-606. doi: 10.1248/cpb.20.1599.

DOI:10.1248/cpb.20.1599
PMID:4639301
Abstract
摘要

相似文献

1
Structure-activity correlations between hydroxamic acids and their inhibitory powers on urease activity. I. A quantitative approach to the effect of hydrophobic character of acyl residue.异羟肟酸与其对脲酶活性抑制能力之间的构效关系。I. 酰基残基疏水特性影响的定量研究方法。
Chem Pharm Bull (Tokyo). 1972 Aug;20(8):1599-606. doi: 10.1248/cpb.20.1599.
2
Quantitative structure-activity relationships between hydroxamic acids and their urease inhibitory potency.异羟肟酸及其脲酶抑制活性之间的定量构效关系。
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Inhibition of urease activity by hydroxamic acid derivatives of amino acids.氨基酸异羟肟酸衍生物对脲酶活性的抑制作用。
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Urease inhibition by hydroxamic acids.
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Study on hydroxamic acids and their urease inhibitory potency by quantum chemistry calculation.
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CoMFA and CoMSIA 3D-QSAR analysis on hydroxamic acid derivatives as urease inhibitors.基于异羟肟酸衍生物作为脲酶抑制剂的比较分子力场分析(CoMFA)和比较分子相似性指数分析(CoMSIA)三维定量构效关系研究
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Inhibition of urease activity but not growth of Helicobacter pylori by acetohydroxamic acid.乙酰氧肟酸可抑制幽门螺杆菌的脲酶活性,但不抑制其生长。
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Inhibition of urease by hydroxamic acids.
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Synthesis, molecular docking and kinetic properties of β-hydroxy-β-phenylpropionyl-hydroxamic acids as Helicobacter pylori urease inhibitors.β-羟基-β-苯基丙酰基羟肟酸的合成、分子对接及对幽门螺杆菌脲酶的抑制动力学研究。
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Molecular modeling studies on the urease active site and the enzyme-catalyzed urea hydrolysis.
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