乙酰氧肟酸可抑制幽门螺杆菌的脲酶活性，但不抑制其生长。
Inhibition of urease activity but not growth of Helicobacter pylori by acetohydroxamic acid.
作者信息
Goldie J, Veldhuyzen van Zanten S J, Jalali S, Richardson H, Hunt R H
机构信息
Department of Laboratory Medicine, McMaster University Medical Centre, Hamilton, Ontario, Canada.
出版信息
J Clin Pathol. 1991 Aug;44(8):695-7. doi: 10.1136/jcp.44.8.695.
Abstract
The in vitro effects of acetohydroxamic acid (AHA), a potent urease inhibitor, were studied to determine the effect on the urease activity and growth of 38 strains of Helicobacter pylori. AHA in concentrations of 50-1000 mg/l had a noticeably reversible inhibitory effect on the urease activity of the organism but no effect on growth.
摘要
对强效尿素酶抑制剂乙酰氧肟酸（AHA）的体外作用进行了研究，以确定其对38株幽门螺杆菌尿素酶活性和生长的影响。浓度为50 - 1000毫克/升的AHA对该菌的尿素酶活性有明显的可逆抑制作用，但对生长无影响。
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