Morgan M H, Read A E
Gut. 1972 Sep;13(9):697-701. doi: 10.1136/gut.13.9.697.
Patients with cirrhosis were found to be extremely sensitive to tranylcypromine, and the use of this drug for the treatment of depression in such patients is contraindicated. Amitriptyline has a wider margin of safety in such patients, but caution is necessary when the higher therapeutic doses are prescribed.