L-脯氨酰-L-亮氨酰-甘氨酸酰胺用于帕金森病的初步临床研究。
Preliminary clinical studies with L-prolyl-L-leucyl-glycine amide in Parkinson's disease.
作者信息
Kastin A J, Barbeau A
出版信息
Can Med Assoc J. 1972 Dec 9;107(11):1079-81.
Abstract
The present study, carried out in 16 parkinsonian patients, indicates that L-prolyl-L-leucyl-glycine amide possesses some antiparkinsonian activity and that, if used with levodopa, it can reduce some of the drug-induced dyskinesias. These preliminary observations should be submitted to a controlled trial in a large number of patients before therapeutic applications are claimed.
摘要
本研究对16例帕金森病患者进行，结果表明L-脯氨酰-L-亮氨酰-甘氨酸酰胺具有一定的抗帕金森病活性，并且如果与左旋多巴联合使用，它可以减轻一些药物诱发的运动障碍。在宣称其具有治疗用途之前，这些初步观察结果应在大量患者中进行对照试验。
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