English T A, Ross J K
Br Med J. 1972 Dec 9;4(5840):598-602. doi: 10.1136/bmj.4.5840.598.
Forty patients with a previous history of bacterial endocarditis were treated surgically between December 1967 and August 1971. Of 28 patients who had elective valve replacements there were four hospital deaths and one late death. Seven patients underwent emergency operation for intractable heart failure before completion of antibiotic treatment, six survived operation and there was one late death. Six patients had operations for infection on pre-existing valve substitutes, of whom three were treated as emergencies. There were two hospital and no late deaths. 78% of all patients were alive and well four years to nine months after operation.These results confirm that in addition to elective valve replacement surgery has an important role both in the treatment of intractable heart failure during the infective stage of bacterial endocarditis and in the eradication of infection on cardiac prostheses.
1967年12月至1971年8月期间，40例有细菌性心内膜炎既往史的患者接受了外科治疗。在28例行择期瓣膜置换术的患者中，有4例住院死亡和1例晚期死亡。7例患者在抗生素治疗完成前因顽固性心力衰竭接受了急诊手术，6例手术存活，有1例晚期死亡。6例患者对已有的人工瓣膜进行了感染相关手术，其中3例作为急诊处理。有2例住院死亡，无晚期死亡。所有患者中有78%在术后4年9个月时存活且情况良好。这些结果证实，除了择期瓣膜置换术外，手术在细菌性心内膜炎感染阶段治疗顽固性心力衰竭以及根除心脏人工瓣膜感染方面均具有重要作用。
